Clears

• FDA has approved an investigational new drug application for synthetic CAR-T (sCAR-T) therapy targeting autoimmune conditions. • The clearance enables clinical trials to test this engineered cell therapy in US patients with refractory autoimmune diseases. • sCAR-T represents a novel approach adapting cancer immunotherapy for immune disorders, potentially offering durable remissions.

• FDA approved Haleon's Narcan 4mg nasal spray for non-prescription sale on April 7, 2026, building on 2023 authorization. • Reversal success rate 98% in trials with 150 US overdose simulations; priced at $29.95 for two-pack. • Addresses 110,000 annual US opioid deaths; 'Lifeline for bystanders,' says FDA Commissioner.

• The Supreme Court issued a ruling clearing the way for the Department of Justice to erase Steve Bannon's January 6 conviction, reversing lower court obstacles to the administration's efforts. • The decision represents a significant legal victory for the Trump administration in its effort to address convictions related to the Capitol riot. • The ruling overturned a district judge's previous injunction that had blocked the administration's actions on the matter.

Planning application expected shortly as London City airport and bank reach agreement for 265m-high buildingBusiness live – latest updatesJP Morgan Chase has reached agreement with London City airport to build one of Europe’s tallest office towers in the east of the capital.The £3bn tower is poised to be the tallest in the Canary Wharf financial district, after JP Morgan, one of Wall Street’s biggest banks, secured approval from the airport. Continue reading...

• NASA's Artemis II mission, the first crewed flight test of the Space Launch System (SLS) rocket and Orion spacecraft, has cleared its final hurdle and remains on track for launch no earlier than April 1, 2026. • The mission will send four astronauts—Reid Wiseman, Victor Glover, Jeremy Hansen, and Christina Koch—on a 10-day orbital test around the Moon, validating systems for future lunar landings. • This milestone follows rigorous technical reviews, ensuring crew safety and vehicle performance after lessons from uncrewed Artemis I in 2022.