Vaccine

• コネチカット州のネッド・ラモント知事は2026年4月28日にHB 5044に署名し、連邦政府の指針に依存せず、州保健局長が独自にワクチン推奨を出す権限を拡大した。 • 本法案には、立法上の議論で大きな論争を巻き起こした州の宗教的自由回復法（RFRA）を明確にする規定が含まれている。 • また、この法律は、ワクチンを拒否する患者を治療した臨床医に対し、保険会社が不利益を課すことを禁止し、医師の診療上の自律性を保護している。

• 最近の研究により、更新されたワクチン製剤が、昨シーズンの健康な成人における救急外来の受診および入院を約50パーセント減少させたことが示されました。 • この大幅な有効性の向上は、ワクチン開発および公衆衛生保護戦略における大きな前進を意味します。 • これらの知見は、2026年4月28日付のCIDRAP最新のワクチン政策状況レポートに記録されている通り、米国におけるワクチン政策の進展に寄与しています。

• A multiyear international campaign is underway to repair damage to childhood immunization efforts caused by the COVID-19 pandemic. • The initiative focuses on restoring vaccination rates that declined during the pandemic period across multiple countries. • Public health experts view this effort as critical to preventing resurgence of vaccine-preventable diseases in vulnerable pediatric populations.

• Health Secretary Robert F. Kennedy Jr., a prominent anti-vaccine voice, praised President Trump's nomination of Dr. Erica Schwartz as CDC Director and expressed his intention to work with her to restore the agency's mission. • Kennedy's public endorsement of the pro-vaccine nominee marked a sharp reversal from his previously hard-line stance on CDC leadership and sparked significant backlash among MAHA (Make America Healthy Again) loyalists online. • The shift comes amid congressional scrutiny of Kennedy's conflicting rhetoric on measles vaccination safety during a Thursday hearing, as measles outbreaks rise across the U.S.

Several shots – including flu and Covid – lost their CDC recommendations under overhauls from the White HouseSeveral shots lost their recommendation from the US Centers for Disease Control and Prevention (CDC) after a judge’s stay against changes wrought by the Trump administration – which may affect access to the shots in some states. And no new vaccine recommendations may be made as long as the vaccines committee is halted.Access to existing vaccines – and the future development of new vaccines – has been increasingly called into question under the second Trump administration, as the now-halted Advisory Committee on Immunization Practices (ACIP) made controversial recommendations and health officials made unilateral changes to routine vaccines, with long-term and global implications. Continue reading...

• A Fred Hutch Cancer Center graduate student presented over 25,000 measurements of influenza-fighting antibodies to WHO scientists via videoconference last fall. • The dataset, published in Virus Evolution, offers near real-time tracking of human immune responses to current flu strains, improving seasonal vaccine composition. • This method addresses gaps in traditional surveillance, potentially enhancing vaccine effectiveness against evolving viruses.

Study that reportedly found reduction in ER visits and hospitalizations being reviewed by Jay BhattacharyaA Trump administration appointee has delayed publication of a Centers for Disease Control and Prevention (CDC) report that shows benefits related to the Covid vaccine, leading to concerns that the administration is engaging in behind-the-scenes tactics to undermine vaccines.Research by CDC scientists found that the Covid vaccine cut the likelihood of emergency room visits and hospitalizations for healthy adults last winter by about half, according to reporting from the Washington Post. The acting CDC director, Jay Bhattacharya, reportedly delayed the report’s publication due to concerns surrounding the research’s methodology. Continue reading...

• The FDA granted approval on April 7, 2026, to Moderna's mRESVIA vaccine, an mRNA-based shot targeting respiratory syncytial virus (RSV) for adults aged 60 and older. • Clinical trials showed 83.7% efficacy against RSV lower respiratory tract disease in the first season, with data from over 37,000 participants across 22 countries including US sites. • This marks the second mRNA RSV vaccine approved after GSK's Arexvy, aiming to reduce 140,000-160,000 annual US hospitalizations among seniors; CDC review expected soon.

NSW follows Queensland, South Australia and Western Australia in offering free treatments for kids four and under, saving up to $70Get our breaking news email, free app or daily news podcastHundreds of thousands of children will be able to access a painless, needle-free flu vaccination for free as governments attempt to curb falling vaccine rates.New South Wales has become the latest state to offer a nasal spray flu vaccine to children for free, following Queensland, South Australia and Western Australia. Continue reading...

Elections seem top-of-mind for the Maha movement as key polling indicates anti-vaccine views are a liabilityUS health officials appear to be shying away from voicing negative views of vaccines in public as November’s midterm elections loom and key polling indicates anti-vaccine views are a liability.Health officials have made unprecedented changes to routine vaccine recommendations in the past year – slashing one-third of the US childhood schedule, including the recommendation for hepatitis B immunization at birth. But even before a federal judge essentially invalidated these moves, officials haven’t championed their dramatic changes after Donald Trump’s pollsters recommended veering away from anti-vaccine ideology ahead of the midterms. Continue reading...

• Pfizer and BioNTech stopped a large US trial of their updated COVID-19 vaccine targeting healthy adults aged 50-64 due to inability to recruit 25,000-30,000 participants without conditions like hypertension or diabetes. • The halt highlights recruitment challenges amid low interest in trials for healthy populations. • This occurs against a backdrop of shifting vaccine policies under the Trump administration, prioritizing chronic disease over broad COVID efforts.

Protesters decried Trump administration healthcare policies and direction of HHS under leadership of RFK JrAs tens of thousands of people assembled across the US and around the world for No Kings protests, about a thousand people gathered outside the National Institutes of Health (NIH) in Bethesda, Maryland, on Saturday morning to protest cuts to medical research and the Trump’s administration’s policies on health.The rally follows a tumultuous year for the research agency, with devastating cuts to multi-year funding and outright terminations of grants, especially to research related to gender and race. The White House is now poised to cut the NIH’s budget by 20%, according to reporting by Roll Call on Friday, nearly one year after mass layoffs at health agencies. Continue reading...

• HHS through the National Cancer Institute announced a $200 million public-private partnership to fund clinical trials for cancer vaccines targeting high-risk recurrence patients. • The initiative supports mRNA and other vaccine types, aiming to accelerate development with private sector involvement including venture capital. • 'Nothing of this scale has been attempted in cancer vaccines before,' said Stacey Adam, VP of science partnerships for the Foundation for the National Institutes of Health.

• Dr. Casey Means' nomination for U.S. surgeon general is stalled after senators from both parties questioned her vaccine views and limited medical experience during a confirmation hearing last month. • The 38-year-old Stanford-educated physician, who left her surgical residency, faces scrutiny for her alignment with Health Secretary Robert F. Kennedy Jr.'s vaccine rollback efforts. • Despite White House and activist support, Means needs full Republican backing on the Senate HELP Committee, but two GOP senators remain opposed amid legal setbacks for Kennedy's agenda.

Judge voids Kennedy’s ACIP picks, leaving key flu, Covid and RSV vaccine recommendations in limboSign up for the Breaking News US email to get newsletter alerts in your inboxAmid upheaval to the US vaccine advisory committee Robert Malone, the former co-chair and controversial figure who has opposed vaccines, says he has been pushed out and won’t be involved in any future decisions. The move comes after a federal judge stayed the appointment of 13 members of the advisory committee on immunization practices (ACIP), essentially invalidating their roles on the committee and the decisions they have made.Those new advisers were all hand-picked by Department of Health and Human Services (HHS) secretary, Robert F Kennedy Jr, after he fired the previous 17 members of ACIP in June – but the judge ruled they were unqualified and not selected properly. Continue reading...

• A federal judge blocked sweeping changes to U.S. vaccine recommendations, including reductions in childhood immunizations and removal of COVID-19 guidance for certain groups, in a lawsuit brought by the American Academy of Pediatrics and other medical groups. • The ruling paused a reconstituted vaccine advisory committee and signals a forthcoming decision on broader legal questions, with the case expected to reach the U.S. Supreme Court soon. • Changes were driven by RFK's authority over federal vaccine policy, which critics argue lack scientific basis and threaten public health.

• The FDA approved the first RSV vaccine for infants via maternal immunization on March 18, 2026, allowing pregnant women to receive vaccination in the third trimester to confer passive immunity to newborns. • The approval is based on a Phase 3 trial showing 82% efficacy in preventing severe RSV disease in infants under six months, with passive immunity lasting approximately three months post-birth. • RSV causes approximately 100,000 hospitalizations and 300-400 deaths annually among US infants, making this vaccine potentially transformative for preventing severe respiratory illness in the most vulnerable population.

Scientific advisory committee to examine impact of offering routine MenB jabs to wider range of peopleThe Kent meningitis outbreak: what is happening and why?Experts are considering expanding the meningitis B vaccination eligibility in response to the fatal outbreak of the disease in Kent.The Joint Committee on Vaccination and Immunisation’s review comes after the health secretary, Wes Streeting, asked it to to “re-examine eligibility for meningitis vaccines” for a wider range of people than those who currently qualify. Continue reading...

• Trump 2.0 policies terminated or overhauled HHS advisory committees, including ACIP with all members replaced in January 2026 by RFK Jr., leading to weakened hepatitis B and COVID-19 vaccine recommendations. • NIH advisory councils have not met, with the director's committee disbanded for over a year; USPSTF has not met since March 2025. • Senator Murray criticized leadership for prohibiting NIH grant processes; new ACIP includes controversial figures like an Alzheimer's patient from the withdrawn aducanumab trial.

• A federal judge on Monday blocked HHS from implementing vaccine policy changes made by RFK Jr.'s revamped CDC Advisory Committee on Immunization Practices (ACIP), reversing all recent decisions. • The ruling leaves unresolved the status of the RSV vaccine for infants, potentially making it no longer free for children who need it, as its inclusion was authorized by the current advisers. • Public health experts are scrambling to understand ramifications, with health groups concerned about unintended harms and weakened vaccination recommendations for hepatitis B and COVID-19.

• The FDA on March 13 expanded approval of GSK's Arexvy RSV vaccine to adults aged 18-49 at increased risk of lower respiratory tract disease. • Phase 3b trial data showed non-inferior immune response in younger adults compared to those 60+, targeting 21 million U.S. adults under 50 with conditions like diabetes or obesity. • RSV causes 17,000 hospitalizations, 277,000 emergency visits, and 2 million outpatient visits yearly in this group, highlighting need for broader protection amid rising cases.

• A federal judge in Massachusetts ruled on Monday to block Health Secretary Robert F. Kennedy Jr.'s recent changes to the nation's childhood vaccine schedule, following a lawsuit by the American Academy of Pediatrics and other medical groups. • The plaintiffs argued that Kennedy's alterations to vaccine recommendations and the influential vaccine advisory committee violated federal law, marking a significant setback to his health policy agenda. • This ruling highlights ongoing tensions between the Department of Health and Human Services and medical organizations over public health guidelines and federal compliance.

• A federal judge in Boston on March 16, 2026, temporarily blocked U.S. health officials from reducing the number of universally recommended childhood vaccines, halting changes announced by HHS Secretary Robert F. Kennedy Jr. in January. • The ruling stems from a lawsuit by the American Academy of Pediatrics and other groups challenging cuts to flu, rotavirus, hepatitis A and B, meningitis, and RSV vaccines, with ACIP meetings postponed as a result. • Medical organizations hailed the decision as restoring science-based policy, while HHS spokesman Andrew Nixon stated 'HHS looks forward to this judge’s decision being overturned,' amid concerns over confusion and weakened protections in 30 states.

Unprecedented changes to routine US immunization recommendations ‘arbitrary and capricious’, court saysSign up for the Breaking News US email to get newsletter alerts in your inboxThe appointment of a controversial slate of vaccine advisers by Robert F Kennedy Jr likely violated federal law, and all votes taken by the committee over the past year have been stayed, a federal judge ruled on Monday.The advisory committee on immunization practices (ACIP) is not able to meet later this week, since its membership has been invalidated, the judge said. Continue reading...

US based Covid vaccine recommendations for children and pregnant people on ideology instead of evidence, critics saySign up for the Breaking News US email to get newsletter alerts in your inboxThere was scant data behind ending the Covid vaccine recommendation for pregnant people and children, according to internal memos made public because of a lawsuit against the US Department of Health and Human Services (HHS).The memos overlooked hundreds of studies on the benefits and safety of Covid vaccination and set the precedent for making changes to vaccine recommendations based on ideology instead of evidence, critics say. Continue reading...

• Gov. Ron DeSantis' proposal to alter Florida's vaccine requirements for school children failed during the 2026 legislative session. • DeSantis promises continued efforts to pass these policies despite the setback and ongoing measles cases rising across the state. • The resolve strengthens public health debates on vaccination mandates amid disease outbreaks in Florida.

The 2025-2026 flu season is concluding with one of the lowest vaccine effectiveness rates in more than a decade, with the CDC reporting effectiveness of approximately 25-30% in preventing adults from needing medical care, according to data released Friday. A viral mismatch between the vaccine strain and dominant H3N2 variant that emerged early winter caused the poor performance, with vaccination proving more protective in children at around 40% effectiveness against medical visits. Despite low effectiveness, the CDC estimates 27 million illnesses, 350,000 hospitalizations, and 22,000 deaths from flu this season—substantially lower than the prior year's 40 million illnesses and 520,000 hospitalizations at the same point.

CDC interim analysis from September 2025 to February 2026 shows this season's flu vaccine effectiveness at 22-34% against outpatient visits for adults and 30-41% for those 65+, with hospitalization protection at 30-31%, due to H3N2 strain mismatch. The season saw 27 million illnesses, 350,000 hospitalizations, and 22,000 deaths, lower than last year's peaks but with 101 child deaths, 85% unvaccinated. Despite flaws, experts like Dr. William Schaffner stress shots prevent severe outcomes, with adult rates at 46.5%. Vaccination campaigns will target improved strains for next season.