Flu Vaccine Effectiveness Reaches One of Lowest Rates in Over a Decade as Season Winds Down
The 2025-2026 flu season is concluding with one of the lowest vaccine effectiveness rates in more than a decade, with the CDC reporting effectiveness of approximately 25-30% in preventing adults from needing medical care, according to data released Friday. A viral mismatch between the vaccine strain and dominant H3N2 variant that emerged early winter caused the poor performance, with vaccination proving more protective in children at around 40% effectiveness against medical visits. Despite low effectiveness, the CDC estimates 27 million illnesses, 350,000 hospitalizations, and 22,000 deaths from flu this seasonβsubstantially lower than the prior year's 40 million illnesses and 520,000 hospitalizations at the same point.
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