Clinical Trials Roundup | 03 July 2026

- Genmab's epcoritamab showed successful results in treating diffuse large B-cell lymphoma (DLBCL), while BRUKINSA achieved a win in treating mantle cell lymphoma (MCL).
- The FDA approved Tregzi for the treatment of graft-versus-host disease (GVHD), providing a critical new tool for patients undergoing allogeneic stem cell transplantation.
- These developments highlight a trend of incremental progress in B-cell malignancies and transplant medicine, contrasting with the continued unpredictability of neuropsychiatric drug development.
- The July 3, 2026, updates signal a shift toward more targeted therapies for long-term transplant complications and specific blood cancers.
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WHO launches first Bundibugyo Ebola drug trials in DR Congo - DongA Science
• The World Health Organization (WHO) has launched the "Partners" clinical trial in the Democratic Republic of Congo to test treatments for the Bundibugyo Ebola virus. • The study will evaluate the efficacy of MBP-134 and remdesivir in up to 1,200 patients currently affected by the outbreak.
Read original · dongascience.com
DongA ScienceClinical trial for Ebola therapies begins in DR Congo
• A randomized platform trial has launched in the Democratic Republic of Congo to evaluate therapies for the Bundibugyo virus, a strain of Ebola with no existing licensed vaccines or treatments. • The study tests whether the monoclonal antibody MBP134, the antiviral drug remdesivir, or a combination of both can improve survival rates across patients of all ages.
Read original · cidrap.umn.eduNew antidepressant prescriptions lower than pre-pandemic levels, study finds - The Pharmaceutical Journal
• A study published in Nature Health on June 15, 2026, reveals that new antidepressant prescriptions in England have fallen below pre-pandemic levels. • The research analyzed primary care dispensing data spanning from 2019 to 2024 to track prescribing trends across the country.
Read original · pharmaceutical-journal.com
The Pharmaceutical JournalEbola treatments trial begins in the Democratic Republic of Congo
• The World Health Organization (WHO) has launched a clinical trial for two Ebola therapeutics in the Democratic Republic of Congo, enrolling the first patient this Thursday. • The trial aims to reduce mortality rates during an outbreak that began in May and has already resulted in 1,406 confirmed cases and 438 deaths.
Read original · bbc.com
BBCTuberculosis Cases in the U.S. Just Hit a Multi-Decade High: Public Health Experts Are Alarmed
• Tuberculosis cases in the U.S. reached a 14-year high in 2024 and remain elevated in 2025, sparking alarm among public health experts. • The surge is attributed to critical gaps in screening and underfunded contact tracing, which leave vulnerable communities exposed to the disease.
Read original · medicaldaily.com
Medical DailyThe U.S. healthcare system is in crisis. A Supreme Court ruling could make things worse
• The U.S. healthcare system is facing a potential crisis as a Supreme Court ruling could pave the way for mass deportations. • Experts warn that these deportations would exacerbate existing staffing shortfalls in hospitals and emergency rooms, with the long-term healthcare sector expected to suffer the most significant disruptions.
Read original · kpbs.orgFDA Expands Moringa Salmonella Outbreak Warning as Recall Grows to 119 Cases Across 36 States
• The FDA updated a Salmonella outbreak warning on June 30, 2026, reporting 119 illnesses across 36 states, including 32 hospitalizations. • The expanded recall now includes products from TNVitamins, Live it Up, Doctor's Pride, and Why Not Natural.
Read original · medicaldaily.com
Medical DailyPatient enrolment begins in a scientific trial to identify the first effective treatments for Bundibugyo virus disease
• The PARTNERS clinical trial has officially opened patient enrolment in the Democratic Republic of the Congo to identify the first effective treatments for Bundibugyo virus (BVD). • This international effort focuses on evaluating potential therapies for Ebola disease specifically caused by the BVD strain, utilizing facilities like the ALIMA Ebola Treatment Centre.
Read original · who.intEbola outbreak reveals unlearned lesson: Early detection is crucial
• A recent Ebola outbreak highlighted critical failures in early detection after weeks were wasted testing for the wrong viral strain. • Infectious disease experts Krutika Kuppalli and Placide Mbala argue that the inability to rapidly identify the specific pathogen hindered effective containment efforts.
Read original · statnews.com
StatnewsFDA news in pediatrics: June 2026
• On June 2, 2026, the FDA approved ensitrelvir for the post-exposure prophylaxis of COVID-19 in patients aged 12 years and older. • The regulatory decision follows positive results from phase 3 clinical trials, confirming the drug's efficacy in preventing infection.
Read original · contemporarypediatrics.comThe United States Could Officially Lose Its Measles-Free Status by November 2026
• The United States risks losing its official measles-free status, which it has maintained since 2000, following a surge to 2,134 cases in 2026. • The Pan American Health Organization (PAHO) will conduct a formal review in November 2026 to determine if the country still meets elimination criteria.
Read original · medicaldaily.com
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