FDA Reports Near-Record New Drug Approvals in Previous Year

• Calls to U.S. poison control centers involving kratom use have increased 1,231% over the past decade, according to a new weekly report from the Centers for Disease Control and Prevention. • The dramatic rise reflects growing kratom consumption among Americans and emerging safety concerns related to the botanical substance. • The trend highlights the need for increased public awareness and clinical guidance regarding kratom's potential health risks and interactions.

• Oklahoma reports 1,218 heart-related deaths per 100,000 residents annually, substantially higher than the U.S. national rate of 920 deaths per 100,000, according to research from Compare the Market. • Heart and vascular diseases rank as Oklahoma's leading cause of death, followed by cancer, accidents and injuries, and respiratory diseases. • America's Health Rankings data shows 11.4% of Oklahoma adults have been told by health professionals they are at risk for cardiovascular disease, placing the state at 43rd out of 50 in cardiovascular risk awareness.

• America's Health Rankings places Tennessee among the bottom ten states for multiple key cardiovascular health indicators, ranking 43rd in high blood pressure prevalence and 45th in high cholesterol rates. • The state's poor cardiovascular health rankings reflect broader public health challenges affecting disease prevention and chronic disease management. • These metrics indicate Tennessee residents face elevated risk for heart disease and related complications compared to national benchmarks.

• CDC reports released in February 2026 show U.S. childhood and teen obesity rates have reached record levels, marking a significant public health concern for younger populations. • The same reports indicate adult obesity rates appear to be plateauing or slowing their growth trajectory, suggesting different demographic trends across age groups. • The findings underscore ongoing disparities in metabolic health across generations and highlight the need for targeted prevention and intervention strategies.

• Jefferson Abington hospital closed its behavioral health unit to accommodate overflow from the emergency department, citing capacity pressures. • The facility will continue providing crisis services and outpatient behavioral health through alternative arrangements, ensuring continuity of care for patients. • The closure reflects broader challenges in the healthcare system regarding bed capacity, mental health service demand, and emergency department overcrowding.

• A Philadelphia cancer patient who had exhausted conventional treatment options was kept alive using a novel T-cell therapy developed and administered at Rutgers Health. • The case represents a breakthrough application of immunotherapy, offering hope to patients facing terminal cancer diagnoses with limited options. • The success demonstrates the therapeutic potential of advanced cellular therapies and highlights Rutgers Health's role in pioneering cutting-edge cancer treatment innovations.

• The American Heart Association released a warning that 60% of US women are projected to develop cardiovascular disease by 2050, reflecting trends in aging populations and risk factor prevalence. • The projection underscores disparities in cardiovascular health outcomes between men and women and highlights the growing public health burden of heart disease. • This forecast emphasizes the need for enhanced prevention strategies, early intervention programs, and targeted health policy initiatives focused on women's cardiovascular health.

• American Medical Association research reveals that over 80% of physicians are integrating AI tools into their clinical practices, reflecting widespread adoption across the medical profession. • Doctors express both optimism about AI's potential benefits and concerns about implementation, emphasizing the importance of physician involvement in AI development and deployment. • The survey highlights the transformative role of artificial intelligence in modern medicine while underscoring the need for continued physician oversight and ethical governance.

• The US measles caseload climbed to 1,671 infections with nearly 100 new cases reported in the past week, according to the CDC's weekly update, with the vast majority occurring in Utah. • Utah recorded 73 new measles cases this week and 142 new cases over the past three weeks, bringing the state's 2026 total to 362 cases compared with 197 for all of 2025. • The outbreak spans 32 states and New York City, with 94% of confirmed cases linked to one of 17 outbreaks; Arizona has 71 total cases, Florida has 129, and Texas has 175 cases.

• The US measles outbreak has accelerated in 2026 with cases now reported in more than half of the states, marking a resurgence 20 years after official eradication, driven primarily by declining vaccination rates. • Last year, the US reported over 2,000 measles cases (2,213 confirmed) and three pediatric deaths, with the mortality rate matching historical data of approximately one death per 1,000 infected children. • Oregon has diagnosed 13 measles cases so far in 2026 with hundreds of potential exposures in the past week; health experts note that official case counts likely underestimate true infection rates due to unreported cases and undetected transmission indicated by wastewater data.

• US poison centers reported a sharp increase in kratom-containing kava exposures from 2000-2025, serving as an early warning for substance harms. • After a 2002 FDA advisory on liver injury, kava reports declined but rose substantially since 2011, now mostly involving men aged 20+ with serious outcomes and co-use with kratom. • Higher rates of severe medical effects underscore risks of increasing popularity and polysubstance use.

• The CDC posted its first large set of genetic data from 1,000 measles viruses circulating in the US last year, with more data expected soon to assess if elimination status has been lost. • In 2025, measles cases reached 2,285 across 44 states—the worst in over 30 years—while 2026 has seen 1,575 cases by late March amid declining vaccination rates. • Delays in data release stemmed from mass layoffs and resignations; researchers criticize the Trump administration's budget cuts and slow outbreak response.