HCA Healthcare Announces New England Journal of Medicine Study Highlighting Advances in CRISPR-based Therapy for Children - BioSpace

• The current Ebola outbreak in Bundibugyo shows a death rate of 26%, which is significantly lower than the 40-70% fatality rate recorded during the 2014–16 West Africa epidemic. • In other health news, the FDA approved Capvaxive on June 18, 2026, for children aged 2-17 with chronic conditions such as heart disease and diabetes.

• Public health experts warn that the U.S. has effectively lost its measles elimination status, as only 6% of 2026 cases are now linked to travel compared to a historical average of 40%. • In other health news, the FDA approved bulevirtide on May 22, 2026, marking the first-ever approved treatment for Hepatitis Delta.

• Bindu Shajan Perappadan reports on several Indian healthcare reforms, including the expansion of QR code-based traceability to vaccines, antimicrobials, and cancer medicines to improve drug security. • The government is introducing measures to simplify drug import procedures for testing, enhancing CGHS financial powers for faster cashless treatment, and launching the PM Family Care Tracker for maternal and child health.

• Paradigm Health formally submitted its response to the U.S. Food and Drug Administration's (FDA) Request for Information (RFI) regarding the Real-Time Clinical Trial (RTCT) Initiative on June 30, 2026. • As the sole technology provider currently operationalizing the FDA's RTCT proof-of-concept studies, Paradigm Health based its submission on insights from biopharma sponsors and healthcare providers.

• The CDC is ending its federal measles diagnostic testing program, shifting the responsibility for these tests to state laboratories. • While state labs already handle the majority of measles testing, critics are alarmed that the loss of federal oversight could impact surveillance and response times.

• Researchers screened over 5,000 compounds and identified 70 existing drugs that effectively suppress Puumala orthohantavirus infections in human cells. • The discovery includes unexpected candidates such as beta-lactam antibiotics, suggesting that repurposed medications can combat the virus.

• Three active investigations in 2026 have linked moringa supplement powders to a multistate Salmonella outbreak. • The outbreak has affected over 119 people across 36 different states, leading to recalls of multiple supplement brands.

• A real-world study conducted in Brazil has demonstrated that the TAK-003 dengue vaccine provides strong protection against hospitalization and symptomatic disease. • The research focused on São Paulo, the epicenter of Brazil's recent epidemic, to test the vaccine's effectiveness outside of controlled clinical trial environments.

• The Bundibugyo virus, a rare orthoebolavirus, remains a significant public health threat due to its ability to cause severe epidemic disease with high mortality rates. • While advances in supportive care have improved patient outcomes, there are currently no licensed vaccines or approved therapeutics specifically designed for the Bundibugyo virus.

• The CDC reports that drug overdose deaths decreased by 13.2% over the most recent 12-month period. • Experts warn this progress is fragile due to the emergence of new synthetic drugs and the use of medetomidine.

• A Salmonella outbreak linked to moringa leaf supplements has expanded to 119 reported cases across 36 U.S. states as of May 2026. • Health officials have issued warnings and multiple brands have recalled affected products to prevent further infections.