HHS Launches $200 Million Initiative for Cancer Vaccine Clinical Trials

• Thousands of CDC employees have been laid off over the past year, leaving the agency in chaos amid funding cuts and the aftermath of a deadly shooting at its Atlanta headquarters last summer. • Insiders express concerns that the incoming Trump-nominated director will further erode trust in the agency as measles outbreaks escalate and vaccine policies face resistance. • The nominee is expected to be announced on Truth Social by Wednesday, inheriting a hollowed-out leadership structure marked by yearlong turmoil.

• An NIH-funded mouse study shows chronic colitis induces long-lasting epigenetic changes in gut stem cells, boosting AP-1 transcription factor activity and tumor growth potential. • Researchers analyzed over 52,000 cells, finding damage memories persist more than 100 days after inflammation ends, heritable across new cells. • The findings from Broad Institute scientists explain how sustained inflammation elevates colorectal cancer risk through dynamic epigenome alterations.

• The White House added Jentadueto, Jentadueto XR for Type 2 diabetes, and Striverdi Respimat for COPD to TrumpRx, enabling cash discounts on brand-name drugs from Boehringer Ingelheim. • Consumers can bypass insurance for lower prices on these medications via the website, expanding access amid high health care costs. • The move supports broader efforts to reduce drug prices as NIH Director Jay Bhattacharya's acting CDC role ends March 26.

• Dr. Casey Means' nomination for U.S. surgeon general is stalled after senators from both parties questioned her vaccine views and limited medical experience during a confirmation hearing last month. • The 38-year-old Stanford-educated physician, who left her surgical residency, faces scrutiny for her alignment with Health Secretary Robert F. Kennedy Jr.'s vaccine rollback efforts. • Despite White House and activist support, Means needs full Republican backing on the Senate HELP Committee, but two GOP senators remain opposed amid legal setbacks for Kennedy's agenda.

• A study analyzing electronic health records from nearly 4 million pediatric hospital admissions from 2016 to 2023 found that 18% of deaths among hospitalized children in the US were linked to sepsis. • Sepsis emerged as a leading cause of mortality in this large dataset, highlighting ongoing challenges in early detection and treatment in pediatric care. • The findings underscore the need for improved sepsis protocols in US hospitals to reduce preventable child deaths, as rates remain significant despite medical advances.

• The House Energy and Commerce Health Subcommittee held a hearing on March 18, 2026, focusing on healthcare providers amid ongoing policy debates. • Reported on March 25, the session examined provider challenges, potentially influencing upcoming health legislation in the US Congress. • This follows recent hearings on Medicare fraud, highlighting congressional scrutiny of healthcare delivery and costs.

• KFF published an update on March 24, 2026, to its tracker monitoring bilateral Memorandums of Understanding (MOUs) under the US America First Global Health Strategy launched September 18, 2025. • These five-year plans (2026-2030) with partner countries aim to transition from US aid to domestic health spending, with implementation starting later in 2026. • The tracker, based on State Department releases and MOU documents, tracks signed agreements to build resilient health systems globally while affecting US policy.

• The Medicare Payment Advisory Commission released its March 2026 Report to Congress, recommending a 0.5% increase in physician payments above current levels. • This proposal aims to address payment updates for Medicare services amid ongoing discussions on healthcare financing sustainability. • The report influences federal policy decisions on Medicare reimbursement rates for physicians across the US.

• Woman’s Hospital in Louisiana launched as the first US site in Baymatob's Oli Study, enrolling over 130 patients to test a wearable sensor for early postpartum hemorrhage detection during labor. • The trial aims to enroll 1000 women across five US sites including University of Colorado, Columbia University, Ohio State, and UPMC Magee-Women’s, with FDA clearance submission planned by year-end. • Postpartum hemorrhage is the leading cause of preventable maternal death globally; pilot results showed promise for the Oli device.

• The US long winter COVID-19 wave is ending with all major metrics showing declines or plateaus in SARS-CoV-2 spread nationwide as of mid-March 2026. • COVID-19 test positivity dropped to 2.5% for the week ending March 14, the lowest since 2022, while emergency department visits for COVID reached just 0.4%. • Cases are declining or likely declining in 45 states per CDC forecasts as of March 17, with flu-like illness visits down 12% to 3.3% and RSV levels also falling.

• House Republicans announced an investigation into rampant hospice fraud in Southern California, alleging tens of millions in taxpayer funds lost to improper payments. • The House Oversight Committee sent a letter to Governor Gavin Newsom requesting documents on state oversight of federally funded hospice programs. • Fraud involves companies receiving payments for ineligible patients, prompting calls for stronger controls amid ongoing healthcare waste concerns.