J&J Psoriasis Pill Receives FDA Approval; Smoking Rate Hits Historical Low

• A STAT national survey reveals NIH funding interruptions are causing layoffs, lab closures, and driving early-career scientists away from research careers due to federal budget and priority changes. • Harvard researcher Josiemer Mattei had her diabetes prevention trial in Puerto Rico terminated in May 2025 when the administration cut over $2.8 billion in grants across the university, forcing her to scramble to relocate the study to avoid losing patients and data. • The NIH remains committed to fully spending its 2026 budget but lags significantly behind prior years in grant awards and disbursements, with researchers reporting taking 95% pay cuts to avoid staff layoffs.

• State officials are warning that spring break 2026 travel season could facilitate the spread of measles across the United States as travelers move between regions with varying vaccination rates. • Health authorities are concerned about potential measles transmission during the high-travel period, with implications for public health preparedness and disease surveillance. • The warning underscores ongoing challenges in maintaining herd immunity and controlling vaccine-preventable diseases during major travel seasons.

• Susie Wiles, White House chief of staff for President Donald Trump, announced on Monday her diagnosis of early-stage breast cancer, caught early with no plans for leave. • She will undergo several weeks of treatment in Washington, D.C., while remaining full-time at the White House. • President Trump stated, 'She will soon be better than ever!' highlighting her continued role amid health challenges.

• A federal judge on Monday blocked HHS from implementing vaccine policy changes made by RFK Jr.'s revamped CDC Advisory Committee on Immunization Practices (ACIP), reversing all recent decisions. • The ruling leaves unresolved the status of the RSV vaccine for infants, potentially making it no longer free for children who need it, as its inclusion was authorized by the current advisers. • Public health experts are scrambling to understand ramifications, with health groups concerned about unintended harms and weakened vaccination recommendations for hepatitis B and COVID-19.

• Trump 2.0 policies terminated or overhauled HHS advisory committees, including ACIP with all members replaced in January 2026 by RFK Jr., leading to weakened hepatitis B and COVID-19 vaccine recommendations. • NIH advisory councils have not met, with the director's committee disbanded for over a year; USPSTF has not met since March 2025. • Senator Murray criticized leadership for prohibiting NIH grant processes; new ACIP includes controversial figures like an Alzheimer's patient from the withdrawn aducanumab trial.

• Researchers from Carnegie Mellon and Northwestern Universities conclude insurer consolidation boosts health insurance premiums in US markets. • About 238 million Americans, or 78% of those insured, rely on private health insurance, increasingly concentrated with examples in Medicare Advantage drawing antitrust attention. • The analysis urges regulation and oversight to address market imperfections from asymmetric information and market power.

• Health workers in Massachusetts lobby for bill making assaults on staff felonies, approved by House last November awaiting Senate vote by July 31. • Violence surged post-COVID per surveys; bill mandates hospitals assess risks and implement ongoing safety policies. • "Health care workers don't feel supported," says Cambridge Health Alliance nursing officer; Sen. Joan Lovely optimistic for passage to reduce assaults.

• The FDA on March 13 expanded approval of GSK's Arexvy RSV vaccine to adults aged 18-49 at increased risk of lower respiratory tract disease. • Phase 3b trial data showed non-inferior immune response in younger adults compared to those 60+, targeting 21 million U.S. adults under 50 with conditions like diabetes or obesity. • RSV causes 17,000 hospitalizations, 277,000 emergency visits, and 2 million outpatient visits yearly in this group, highlighting need for broader protection amid rising cases.

• The FDA linked Raw Farm's raw cheddar cheese to seven E. coli O157:H7 cases across multiple states, a strain causing severe kidney issues, hospitalization, or death. • Producer declined recall of two products despite Sunday's FDA alert on March 16. • Outbreak underscores risks of raw milk products, prompting public warnings to avoid consumption.

• Federal grant funding for FQHCs stayed flat from 2019-2023 while health care costs rose over 25%, leading to negative margins of 2.1% by 2024. • An estimated 11.8 million Americans will lose Medicaid coverage due to $344 billion cuts over the next decade, overwhelming FQHCs with uninsured patients. • Recent closures include a New Hampshire rural site in 2025 and six South Carolina locations last year due to shortfalls.

• The NYC Health Department issued an advisory confirming the first severe mpox clade I case in a city resident, marking the initial detection of this more virulent strain in New York. • Mpox clade I is one of two main genetic groups of the virus, known for causing more severe illness compared to clade II. • This development raises concerns for public health monitoring and response in urban areas amid ongoing global mpox transmission risks.