Milestone Pharmaceuticals' CARDAMYST Nasal Spray Added to Express Scripts National Formularies

• Bluestem Health in Lincoln, Nebraska, serving 21,000 low-income and uninsured patients, has operated at a loss for two years and anticipates worsening conditions due to new Medicaid work rules under President Trump's One Big Beautiful Bill Act. • Nebraska becomes the first state to enforce work requirements for certain Medicaid enrollees, risking coverage loss and threatening clinic viability, as stated by CEO Brad Meyer. • The policy darkens the outlook for government-backed clinics nationwide by reducing patient access to care amid rising operational costs.

• Soligenix's HyBryte for cutaneous T-cell lymphoma (CTCL) has a second Phase 3 trial underway with enrollment of approximately 80 subjects, interim analysis in Q2 2026, and top-line results in H2 2026. • Previous Phase 3 trials showed statistical significance in primary endpoints across multiple cycles, following FDA NDA submission and RTF letter. • The program targets unmet needs in rare dermatological cancers with ongoing FDA discussions for development path.

• Congress reauthorized the Dr. Lorna Breen Health Care Provider Protection Act, extending mental health support programs for healthcare professionals through September 2030. • Named after emergency physician Dr. Lorna Breen, who died by suicide during the COVID-19 pandemic, the law addresses burnout among nurses and others. • The legislation continues federal initiatives to improve workplace conditions and reduce mental health challenges in healthcare.

• US healthcare costs for employers are forecasted to increase more than 9% in 2026, driven by regulatory changes, labor shortages, and rising demand. • Growing use of specialty drugs, particularly GLP-1 medications for weight loss and diabetes, significantly contributes to the cost surge. • Businesses face pressure to redesign benefits packages amid these economic pressures on public health spending.

• A new report warns that hundreds of hospitals serving 6.6 million Americans in 44 states and Washington, D.C., face serious threats from potential Medicaid cuts. • The cuts could force hospitals to reduce services or close, severely impacting healthcare access for lower-income and underserved communities. • Medicaid remains a critical funding source for these facilities, highlighting the broad national implications for public health infrastructure.

• A stepwise hypertension medication algorithm, the UC Way, adopted across University of California's six academic medical centers, boosted blood pressure control from 68.5% to nearly 74% among 90,000 patients. • Among 11,500 UCSF patients, the improvement averted 72 strokes, 48 heart attacks, and 38 deaths, according to a two-year study ending mid-2025. • Developed by multidisciplinary UC Health experts and integrated into electronic health records since 2023, the tool allows customized treatment adjustments.

• The share of Affordable Care Act customers in plans exceeding $6,000 yearly doubled following expiration of Covid-era assistance, signaling household budget pressures. • US Centers for Medicare and Medicaid Services data shows 2026 enrollment fell 5% to 23.1 million, with further drops expected from premium non-payers. • This cost surge underscores ongoing affordability challenges in the Obamacare marketplace post-subsidy end.

• CMS announced the Accelerating State Pediatric Innovation Readiness and Effectiveness Model (ASPIRE), a 10-year voluntary program for up to five states. • ASPIRE targets Medicaid and CHIP enrollees up to age 21 with complex medical and behavioral needs through early identification, care coordination, and quality accountability. • A Notice of Funding Opportunity will be released later this year to solicit state participation.

• Last August, the Trump administration ordered states to reverify immigration status of hundreds of thousands of Medicaid enrollees, but findings from five states show few immigrants without legal status improperly receiving benefits. • States paid Deloitte and other firms millions to comply with the law aimed at cutting Medicaid rolls, with federal officials mandating reverification of enrollee immigration data. • The reviews highlight limited evidence of widespread ineligibility, raising questions about the policy's effectiveness and costs to update systems amid ongoing crackdowns.

• Health savings account companies, benefiting from Trump's tax bill, formed the Great American Health Alliance (GAHA) dark money group to push for further HSA expansions. • The lobbying effort aims to broaden tax advantages amid growing industry influence in policy debates. • Critics highlight potential risks of prioritizing industry gains over consumer protections in health financing.

• The Guttmacher Institute released a report showing U.S. abortion rates have remained largely steady despite strict bans in 13 states. • Travel for abortions has declined as telehealth access increases, with data scientist Isaac Maddow-Zimet noting, 'It makes sense that we'd see a decline in travel for abortion.' • The findings highlight shifts in care delivery amid policy changes, impacting access in states like Illinois, Maryland, and New York.