UK government axes flagship global health project

Oxford team’s technology picked up danger signs with 86% accuracy in study of 72,000 patients in EnglandOxford scientists have developed a simple AI tool that can predict the risk of heart failure five years before it develops.More than 60 million people worldwide have the condition in which the heart cannot pump blood around the body as well as it should. Spotting cases before they develop into heart failure would be a big step forward, experts say. Doctors could prepare better for and manage the condition at an earlier stage or even prevent it entirely. Continue reading...

Estimated 2,000 ships, including oil and gas tankers and cruise liners, remain trapped in the Persian Gulf since start of warThere will be no “mass exodus” of ships through the strait of Hormuz, according to shipping analysts, despite the agreement of a two-week conditional ceasefire between the US and Iran and provisions for a temporary reopening of the crucial maritime channel.The ceasefire agreement “doesn’t change the situation in the sense that Iran is still in control,” said Richard Meade, the editor-in-chief at maritime data provider Lloyd’s List Intelligence. “It still requires ships to essentially seek permission, and that’s the key. That means that nothing has changed – no permission, no transit.” Continue reading...

Jason Tarry sees salary increase by 21% in year to January, while fewer people are employed at John Lewis and Waitrose storesThe boss of the group that owns John Lewis and Waitrose was handed a 21% increase in basic pay last year to £1.2m while the retailer cut 3,300 jobs.Jason Tarry, who became chair of the John Lewis Partnership (JLP) in September 2024, saw his annual salary increase by a fifth to £1.2m in the year to January, from £990,000. Continue reading...

Marist poll shows that 48% of city residents approve of Mamdani’s performance while 55% view him favorablySign up for the Breaking News US email to get newsletter alerts in your inboxAs New York City’s mayor, Zohran Mamdani, approaches his first 100 days in office, a new survey shows that roughly half of city residents approve of his performance so far.The poll, conducted by the Marist Institute for Public Opinion and released on Wednesday morning, found that 48% of residents say they approve of the job Mamdani, 34, is doing, while 30% disapprove and 23% remain unsure. Continue reading...

Former Channel 4 chair and boss of Kingfisher to be appointed at crucial time for UK’s media regulatorBusiness live – latest updatesThe UK media regulator Ofcom has named the City veteran Ian Cheshire as its next chair.Ofcom, which oversees the UK’s media and internet sectors, named Cheshire as its preferred candidate for chair on Wednesday. He will be formally appointed to the role for a four-year term once he has been approved in a parliamentary hearing. Continue reading...

Much is expected of Online Safety Act and less from free speech advocates leaving new boss in difficult placeIan Cheshire’s Ofcom intray is big. It is available online under the regulator’s plan for 2026/27 and covers an array of industries: telecoms; broadband; the postal service; media and the online world.It is the latter that it going to dominate his tenure. Ofcom oversees the Online Safety Act, the legislation that regulates social media in the UK. Much is expected of the act from internet safety campaigners, and a bit less from freedom of speech advocates, which leaves Cheshire in a difficult place. Continue reading...

Specialist lender says it expects its slice of £9.1bn compensation set by FCA to be about £320mClose Brothers shares surged on Wednesday after the UK bank declared it could “comfortably absorb” its slice of a £9.1bn compensation bill over the motor finance scandal, hours after one of its rivals announced it was selling its UK operations over looming costs.The specialist lender said it expected the final terms of the Financial Conduct Authority’s (FCA) compensation scheme to cost roughly £320m, a sum that is “broadly similar” to previous estimates and the £294m put aside to date. Continue reading...

Exclusive: Capital’s mayor warns people not to use next month’s elections as a referendum on Labour’s progressUK politics live – latest updatesSadiq Khan has said he can understand why some former Labour voters are “flirting” with other parties in the run-up to May’s elections, but said that they may regret seeing a Green or Reform-led council in their areas.Speaking to the Guardian at a youth centre, where he was announcing new funding for facilities for young people, the London mayor also cautioned Labour MPs against considering a challenge to Keir Starmer, saying such “navel gazing” would be punished by the electorate. Continue reading...

New administration reverses expropriation of property founded by ex-Nazi Paul Schäfer, leaving victims in limboWith its Germanic crosses and colourful toy-town facades, the village square of the tiny Chilean settlement of Villa Baviera gives little indication of the horrors of its past.Until 1991, this cattle town of a few hundred people was a compound known as Colonia Dignidad. Its leader, Paul Schäfer, a former Nazi and weapons smuggler, bought a swathe of land in the valley in 1961, eventually holding as many as 300 people in a fenced enclave with minimal contact with the outside world. He sexually abused and even tortured the children in the camp. Continue reading...

Struggling pubs reel from rising business rates, wages and energy bills, with customers at limit of what they will payNick Evans is staring in vain at columns of numbers, trying to make them add up to a profit. He is a co-owner of the Old Crown Coaching Inn in Faringdon, Oxfordshire, a pub and hotel whose rich history is etched into its crooked wooden beams and cosy snugs.Oliver Cromwell stayed here in 1645. A room believed to have been used by the notoriously severe “hanging judge” Lord Jeffreys to condemn rebels now stages happier encounters: it is the honeymoon suite. Continue reading...

Lawyers for Robert Morales’s family said chatbot ‘may have advised the shooter’ on how to carry out shootingThe family of a man who was killed at Florida State University last year plans to sue ChatGPT and its parent organization, OpenAI, for allegedly telling the accused gunman how to carry out the mass shooting.Lawyers for the family of Robert Morales wrote in a statement they had learned the shooter was in “constant communication with ChatGPT” ahead of the shooting, and that the chatbot “may have advised the shooter how to commit these heinous crimes”. Continue reading...

Executive complaints unit finding relates to broadcast of N-word during awards ceremonyThe BBC breached its editorial standards by broadcasting a racial slur during the Bafta film awards ceremony in February, the corporation’s executive complaints unit has found.More details soon … Continue reading...