What went right this week: the good news that matters - Positive News

- Researchers are launching a clinical trial to determine if the experimental drug trontinemab can prevent people with high p-tau217 levels from developing dementia.
- The study aims to recruit 1,600 participants following previous research showing the drug cleared amyloid plaques, a hallmark of Alzheimer's, in 90% of early-stage patients.
- A successful outcome could provide a preventative medical treatment for individuals at high risk of cognitive decline before symptoms appear.
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Abortion bans make ‘evidence-based medicine’ impossible in some cases, new report says | Abortion
• The Society for Maternal-Fetal Medicine released a statement on Tuesday arguing that abortion care is a core component of maternal-fetal practice. • The report notes that 41 states currently ban abortion at some point during pregnancy.
Read original · theguardian.comClinical Trial of the Oral Drug NV-387 to Treat Ebola to Start Next Week, Hoping to Reduce Fatalities and Spread, As the Largest Ebola Outbreak is Expanding in ?DR Congo with 48% Crude Fatality Rate, Says NanoViricides
• NanoViricides will begin a Phase II clinical trial next week for NV-387, an oral gummy drug designed to treat the Bundibugyo Ebola virus. • The trial responds to an expanding outbreak in the Democratic Republic of Congo where the crude fatality rate has reached 48%.
Read original · investingnews.com
Investing News NetworkWHO expresses cautious optimism about bid to control Ebola outbreak in DRC
• The World Health Organization expressed cautious optimism regarding the trajectory of the current Ebola outbreak in the Democratic Republic of the Congo. • This event is the second largest Ebola outbreak on record, though overall case counts remain high.
Read original · statnews.com
StatnewsConnect Biopharma Asthma Trial Reduces Failures 66%
• Connect Biopharma reported that its asthma trial reduced failures by 66% based on recent patient data. • Lung function improved by 250 mL by Day 7 compared to 120 mL for the placebo group among 160 patients.
Read original · stocktitan.net
Stock TitanThird Measles Death in Pennsylvania as 693 Cases Spread and CDC Help Is Refused
• An unvaccinated 40-year-old woman in Jefferson County, Pennsylvania, died from measles complications in 2026. • Pennsylvania has recorded 693 confirmed cases across 38 counties and has refused the CDC Epi-Aid outbreak assistance that six other states requested.
Read original · easternherald.comUS push to cut drug prices could mean longer waits for European patients
• A new modelling study published in The Lancet suggests European patients may face longer waits for new medicines due to US efforts to lower drug prices. • Researchers analyzed 195 patented medicines that represent $87.9 billion of annual spending in the United States.
Read original · euronews.com
EuronewsPsychedelic treatments move closer to mainstream at FDA
• The Food and Drug Administration is seeking public input on the potential for supervised therapeutic use of psychedelic drugs. • Current federal laws classify hallucinogens like psilocybin and MDMA as Schedule I drugs, meaning they are legally defined as having no accepted medical use.
Read original · washingtontimes.comClinical Trial of the Oral Drug NV-387 to Treat Ebola to Start Next Week, Hoping to Reduce Fatalities and Spread, As the Largest Ebola Outbreak is Expanding in DR Congo with 48% Crude Fatality Rate, Says NanoViricides - BioSpace
• NanoViricides will begin a clinical trial next week for the oral drug NV-387 to treat an expanding Ebola outbreak in the Democratic Republic of Congo. • The current outbreak of the Bundibugyo Ebolavirus variant has a 48% crude fatality rate and no approved treatment or vaccine.
Read original · biospace.comMisinformation, hesitancy could blunt impact of new cancer vaccines • Stateline
• Medical researchers are warning that misinformation and vaccine hesitancy could limit the effectiveness of upcoming personalized cancer vaccines. • These vaccines are designed to prevent cancer from returning by training the immune system to recognize specific proteins on a patient's tumor.
Read original · stateline.orgScholar Rock wins FDA approval for first drug to target SMA muscle loss
• The FDA approved Scholar Rock's drug Isembyld for adults and children aged 2 and older who are already using therapies for spinal muscular atrophy (SMA). • A late-stage clinical trial showed that patients using Isembyld alongside an SMN2-targeting drug improved their motor skills after one year, while the placebo group declined.
Read original · statnews.com
StatnewsRare disease reform, CMC risk, reshoring US trials top of mind ahead of PDUFA VIII meeting - BioSpace
• The FDA is meeting this Wednesday to gather input from the public and industry stakeholders for the next Prescription Drug User Fee Act, which will set agency priorities for fiscal years 2028–2032. • Health policy firm Aviva Strategies noted in a Friday memo that the FDA's Rare Disease Innovation Hub is working to align the Center for Drug Evaluation and Research and the Center for Biologics Evaluation and Research.
Read original · biospace.com