Cancer Patients

• Researchers at UCL and UCLH conducted a trial where patients with stage 2 or 3 colorectal cancer received just nine weeks of pembrolizumab immunotherapy before surgery, challenging the standard approach of surgery followed by months of chemotherapy. • Early results showed 59% of patients had no detectable cancer after completing immunotherapy and undergoing surgery, and after 33 months of follow-up, none of the patients have experienced a relapse. • This outcome represents a significant shift in colorectal cancer treatment protocols, suggesting that short bursts of targeted immunotherapy prior to surgery may deliver more durable results than conventional post-operative chemotherapy regimens.

Injectable pembrolizumab can treat several types of cancer and can be administered in under two minutesThousands of patients across England each year will benefit from a new immunotherapy treatment that can be used for several types of cancer, the NHS has announced.The injectable form of pembrolizumab, which can be administered in under two minutes, kills cancer cells by blocking a protein called PD-1, which acts as a brake on immune responses, allowing the immune system to recognise and attack cancer cells. Continue reading...

Exclusive: Pre-chemotherapy tests previously did not look for gene variant that put some ethnicities at higher risk of serious side effectsThousands of cancer patients from minority ethnic backgrounds will have access to “groundbreaking” genetic testing on the NHS that previously discriminated against them.This routine form of genetic testing, used before chemotherapy treatment, could save the lives of Black and minority ethnic cancer patients who already face poorer health outcomes after diagnosis compared with their white counterparts. Continue reading...

PhenMap tool could spare thousands of patients from treatment that would be ineffective for themA new AI-driven way of identifying how patients with advanced bowel cancer will respond to a drug that was recently introduced by the NHS has been announced.Researchers at London’s Institute of Cancer Research and the RCSI University of Medicine and Health Sciences in Dublin have developed the method with the goal of sparing potentially thousands of patients from being given drugs that would be ineffective in fighting their cancers. Continue reading...