• Pfizer and BioNTech stopped a large US trial of their updated COVID-19 vaccine targeting healthy adults aged 50-64 due to inability to recruit 25,000-30,000 participants without conditions like hypertension or diabetes.
• The halt highlights recruitment challenges amid low interest in trials for healthy populations.
• This occurs against a backdrop of shifting vaccine policies under the Trump administration, prioritizing chronic disease over broad COVID efforts.
• A new COVID variant is under monitoring as medical experts assess potential health risks and transmission patterns.
• Dr. Alok Patel of Stanford Children's Health discussed emerging trends in AI-driven health advice and its growing adoption among patients.
• The simultaneous focus on variant surveillance and AI health tools reflects evolving healthcare delivery and disease monitoring approaches.
Iran conflict could see shortages not just in fuel, but fertiliser and fossil fuel resins – used to make milk bottlesGet our breaking news email, free app or daily news podcastFarmers say Australian consumers could pay more for everyday staples for the next year at least as a result of the US-Israel war on Iran.But the CEO of dairy farmer cooperative Norco, Michael Hampson, says a six to 12 month disruption to food supply is likely a best-case scenario, depending on the strait of Hormuz reopening soon and global petrochemical supply chains beginning to stabilise. Continue reading...
• The US long winter COVID-19 wave is ending with all major metrics showing declines or plateaus in SARS-CoV-2 spread nationwide as of mid-March 2026.
• COVID-19 test positivity dropped to 2.5% for the week ending March 14, the lowest since 2022, while emergency department visits for COVID reached just 0.4%.
• Cases are declining or likely declining in 45 states per CDC forecasts as of March 17, with flu-like illness visits down 12% to 3.3% and RSV levels also falling.
• Peer-reviewed research in Science Advances identifies 155,000 uncounted COVID-19 deaths in 2020-2021, raising official U.S. toll from 840,000 to nearly 1 million that period.
• AI analysis of mortality data shows 16% undercount, totaling 1.2 million U.S. COVID deaths over six years.
• Undercounts disproportionately affect Hispanic and communities of color, often from non-hospital deaths, impacting public health policy accuracy.
How infections linked to a nightclub escalated into a public health incident requiring a national response is a puzzle experts are still grappling withTyra Skinner had already been violently sick three times when doctors at Kent’s William Harvey hospital realised something was badly wrong. The 20-year-old was rushed into critical care, racked with a pounding headache, a stiff neck and excruciating pain – the hallmark symptoms of meningitis, the disease that had already claimed two young lives in Kent.“She could hardly move, she was in a foetal position. She was so cramped up and sore,” her father, Dale Skinner, 42, told the Guardian. “It was horrendous, to be honest, to see her so helpless and in so much pain.” Continue reading...
In today’s newsletter: Bereaved families say the latest findings confirm long-standing concerns about capacity, care and political choicesGood morning. Yesterday lunchtime the UK Covid-19 inquiry published its latest findings – this time on how the NHS, its staff and patients were affected during the pandemic. It delivered a stark verdict: the health service “teetered on the brink of collapse” and only avoided it through the “almost superhuman efforts” of staff.Heather Hallett, the inquiry chair, said healthcare systems “coped, but only just” – and rejected the claim made by Conservative ministers at the time that the NHS had not been overwhelmed. For bereaved families, that language matters.Middle East | Iran said it would show “zero restraint” if its energy infrastructure was targeted again as Qatar revealed that almost a fifth of its liquefied natural gas export capacity had been knocked out in an Iranian strike.Health | Meningitis vaccination has been expanded in Kent after cases linked to a Canterbury nightclub rose to 27. Two people have died, and officials say the outbreak is being contained.Politics | Muslim leaders have condemned Nigel Farage’s call to ban public prayer by Muslims in the UK as bigoted and warned of a “growing tide of hate” after Kemi Badenoch questioned whether the events fitted “within the norms of British culture”.EU | EU leaders have pledged to stand behind Cyprus as it seeks “an open and frank discussion” on the future of the British bases on the island, which have become a target after the outbreak of the latest Middle East crisis.Immigration | A 16-year-old schoolgirl is stranded in Denmark after she was not allowed to board a flight to the UK due to new border rules on dual nationals. Continue reading...
• Researchers using AI analyzed death certificates and estimated 155,000 additional unrecognized COVID-19 deaths outside hospitals in 2020-2021, raising the official toll of 840,000 by 16%.
• The study compared symptomology of hospital deaths with those outside care, highlighting dramatic disparities in uncounted fatalities nationwide.
• This undercounting underscores ongoing challenges in pandemic mortality tracking and public health surveillance across the U.S.
Chair Heather Hallett says pandemic had devastating impact due to NHS being in ‘parlous state’ at timeThe NHS “teetered on the brink of collapse” during the Covid pandemic, and only just coped thanks to the “superhuman” efforts of healthcare workers, an official inquiry has concluded.In a damning assessment of how the UK’s healthcare systems coped with the pandemic, the Covid-19 inquiry chair, Heather Hallett, said the impact was “devastating” due to the NHS being in a “parlous state” before the outbreak of the virus.The NHS entered the pandemic with low bed numbers, high numbers of staff vacancies and high bed occupancy, meaning it was already in a “precarious position” and ill-prepared to deal with a pandemic.There was not enough PPE at the start of the pandemic, meaning healthcare workers had to put themselves and their families at risk to care for patients.Infection control in the early stages of the pandemic was flawed as it assumed Covid-19 was spread by physical contact, rather than being airborne.The “stay home, protect the NHS, save lives” public message may have inadvertently led to a decline in hospital attendance of life-threatening emergencies such as heart attacks.80% of healthcare professionals said they acted in a way that conflicted with their values during the pandemic, with some saying they felt they were “playing God” as they were unable to give everyone the treatment they needed. Continue reading...
Finding suggests as many as 155,000 deaths, likely occurring outside of hospitals, not recognized at Covid relatedThe Covid-19 pandemic’s early death toll was much higher than the official US count, according to a new study that spotlights dramatic disparities in the uncounted deaths.About 840,000 Covid-19 deaths were reported on death certificates in 2020 and 2021. But a group of researchers – using a form of artificial intelligence – estimate that as many as 155,000 unrecognized additional deaths likely occurred in that time outside of hospitals. That would mean about 16% of Covid-19 deaths went uncounted in those years. Continue reading...
US based Covid vaccine recommendations for children and pregnant people on ideology instead of evidence, critics saySign up for the Breaking News US email to get newsletter alerts in your inboxThere was scant data behind ending the Covid vaccine recommendation for pregnant people and children, according to internal memos made public because of a lawsuit against the US Department of Health and Human Services (HHS).The memos overlooked hundreds of studies on the benefits and safety of Covid vaccination and set the precedent for making changes to vaccine recommendations based on ideology instead of evidence, critics say. Continue reading...
Class action settles after retailers argued state government should pay them for economic loss resulting from pandemic lockdown Businesses affected by one of the world’s longest Covid-19 lockdowns will receive $125m from taxpayers after a state government agreed to settle the matter.A class action was brought in the supreme court on behalf of businesses affected financially by Victoria’s 2020 lockdowns. Continue reading...
The United States commemorates six years since President Donald Trump declared a national COVID-19 emergency on March 13, 2020, when nearly 2,000 Americans were infected, marking a pivotal shift to a 'new normal' with ongoing mysteries in long COVID and vaccine developments. A meta-analysis shows long-COVID prevalence at 29% overall, dropping to 23% post-Omicron, with Omicron linked to brain fog and paresthesia while earlier variants caused shortness of breath and loss of smell. Severe COVID-19 and flu infections prime lungs for cancer development months or years later, but vaccination prevents these effects, per UVA Health research. Hospitals continue facing nursing shortages, with over 138,000 nurses leaving since 2022 due to pandemic stress.
The United States commemorates six years since President Donald Trump declared a national COVID-19 emergency on March 13, 2020, when nearly 2,000 Americans were infected, marking a pivotal shift to a 'new normal' with lasting impacts on healthcare. A meta-analysis shows long-COVID prevalence at 29% overall, dropping to 23% after Omicron dominance, with Omicron linked to brain fog and paresthesia while earlier variants caused shortness of breath and loss of smell. Severe COVID-19 and flu infections can prime lungs for cancer development months or years later, but vaccination prevents these effects, per UVA Health research. Hospitals continue facing a nursing shortage, with over 138,000 nurses leaving since 2022 due to pandemic-related stress.