Deepens

• Reuters reported on May 16 that U.S. President Donald Trump’s coercive diplomacy toward Iran has “hit a wall,” with the two sides deadlocked after weeks of public threats and ultimatums. • The standoff is linked to an 11-week-old crisis that has shaken the global economy, with analysts warning that energy supplies and markets could face prolonged disruption if talks do not move forward. • Trump is said to be insisting on emerging from any deal as an outright U.S. victory, while Iran is unlikely to accept what it sees as total defeat, complicating compromise.

Dr Tracy Beth Høeg, the Food and Drug Administration’s top drug regulator, says she was fired from agency after declining to resignIn a major shake-up at the US Food and Drug Administration (FDA), top regulators left on Friday – including Tracy Beth Høeg, the acting drug chief, who says she was fired, and Katherine Szarama, the acting vaccines chief who has only been in the position for days. Jim Traficant, the chief of staff, has also been ousted.The FDA now has no permanent commissioner or deputy commissioner and no permanent leaders of two major centers, after the resignation of Marty Makary on Tuesday and other high-profile departures. Continue reading...

• SoftBank announced a deepened push into AI through a new venture involving OpenAI, targeting enterprise applications in the US market. • The move comes as rival venture capital firms increase funding for AI startups, intensifying competition for talent and tech. • This investment bolsters SoftBank's position in the booming US AI sector, potentially accelerating model deployments.

Motorists are forced to queue up to six hours for fuel or pay more on the black market, while farmers lack fuel to operate machinery and harvest crops.

• Egypt has convened an emergency regional summit with Ethiopia, Sudan, and other Nile Basin nations to address water allocation disputes intensified by Sudan's ongoing civil war and dam infrastructure threats. • The summit, held in Cairo on Friday, focused on protecting the Grand Ethiopian Renaissance Dam and Blue Nile water flows during heightened regional conflict; negotiations remain deadlocked. • US officials are monitoring the summit closely, concerned that water scarcity could fuel refugee crises across the Horn of Africa and destabilize a critical US partner region.

• The World Food Programme declared a humanitarian emergency in Ethiopia's Somali and Afar regions Friday, warning that sustained drought has destroyed crops and livestock herds, leaving 9.4 million people facing acute food insecurity. • Local authorities reported a 60% crop failure compared to last year; malnutrition rates among children under five have climbed to 18%, approaching famine thresholds, WFP spokesperson stated. • The organization called for immediate international funding to deliver emergency rations and establish feeding centers, noting that conflict in neighboring regions has already strained Ethiopia's humanitarian response capacity.

• Israeli and Egyptian officials held talks in Cairo on April 18 to discuss a potential ceasefire agreement brokered by Qatari mediators, marking the first substantive negotiation in three weeks following escalated border tensions. • Gaza's health ministry reports 1.8 million people face acute food insecurity, with humanitarian organizations warning of disease outbreaks; the UN humanitarian coordinator called the situation "the worst in two years." • Both sides remain divided over prisoner exchanges and Israeli military withdrawal timelines, though preliminary frameworks for a phased 90-day truce have been proposed.