Participants who got single dose of psilocybin were more likely to abstain from cocaine than those who got placeboResults from a new clinical trial show that a single dose of psilocybin could be an effective treatment for cocaine addiction.The study, published in Jama Network Open this month, showed that 19 participants who received a single dose of psilocybin were more likely to abstain from cocaine than 17 participants who received a placebo of diphenhydramine, a common antihistamine. Continue reading...
Mirroring of each other’s attire may signal alignment – though the look wasn’t a huge departure for either leaderWhen Donald Trump and Xi Jinping met for a welcome ceremony in Tiananmen Square this week with the world’s gaze on them, they mirrored one another in strikingly similar suits.Both were blue, single-breasted with flap pockets. Both had two buttons with only the top one done up. Both wore red ties. Continue reading...
Powerful property and farming firm Grosvenor Group says knock-on effect of Iran war could arrive next yearFertiliser shortages caused by the Iran war have driven up costs for UK farmers by up to 70% and will have a “dramatic” impact on food prices globally next year, according to one of Britain’s most powerful property and farming companies.Mark Preston, executive trustee of the 349-year-old Grosvenor Group, controlled by the Duke of Westminster, said fertiliser “was already quite expensive” before the 50% to 70% surge in prices since the start of the Iran war in late February. Continue reading...
Researchers say findings are not reason to shy away from restrictions as MPs consider ban in England’s schoolsStrict bans on mobile phones in schools have “close to zero” impact on student learning and show no evidence of improvements in attendance or online bullying, a study has found.Researchers at US universities including Stanford and Duke looked at nearly 1,800 US schools where students’ phones were kept in locked pouches and found little or no differences in outcomes compared with similar schools without strict bans. Continue reading...
Mark Rowley defends officers who arrested suspect in Wednesday’s incident and calls on Green party leader to show solidarity The Metropolitan police chief has said that Green party leader Zack Polanski sharing a post about the arrest of the Golders Green terror suspect will have a “chilling effect”.Met officers arrested a 45-year-old man after two Jewish people were stabbed in the suburb of north-west London on Wednesday. Police said the suspect was shot with a stun gun to subdue him. Continue reading...
Iran’s goal is to maintain chokehold on global economy even as some say it could run out of oil storage by SundayMiddle East crisis – live updatesDonald Trump’s indefinite shelving of the plan to bomb Iran’s bridges and power station on Tuesday night is being widely described as leaving the conflict in limbo, but that is anything but the truth.Pakistan insists the prospect of talks in Islamabad has not evaporated, and positive messages are still being exchanged, but in the meantime the site of kinetic activity has switched from land to sea. Both sides are vying to prove they can enforce their blockade of the strait of Hormuz more effectively than the other. It has become a form of gunboat diplomacy brought to life in the most significant geopolitical waterway in the world. Continue reading...
Firm had to repatriate almost 12,000 guests and staff, including from two cruise ships in Abu Dhabi and DohaThe Iran war has cost the travel company Tui €40m (£34.7m) so far, including repatriating almost 12,000 holidaymakers and staff, and forced it to cut its profit forecast for this year.Europe’s biggest holiday operator said that it had taken the hit in March owing to the impact of the conflict in the Middle East, as it was forced to bring home 5,000 guests from two cruise ships anchored in ports in Abu Dhabi and Doha. Continue reading...
António Guterres welcomes truce and says through spokesperson he hopes halt in fighting will ‘pave the way for negotiations’Hello and welcome to our live coverage of events in the Middle East.United Nations chief António Guterres has welcomed the ceasefire announced on Thursday between Israel and Lebanon, urging “all actors” to fully respect the truce.A 10-day ceasefire between Israel and Lebanon has come into effect, pausing fighting in a devastating conflict between Israel and Hezbollah that has killed more than 2,100 Lebanese people and displaced more than 2.1 million. The agreement was announced earlier by Donald Trump, who said he had spoken with Israeli prime minister Benjamin Netanyahu and Lebanese president Joseph Aoun, and invited both leaders “for meaningful talks” at the White House. Both leaders welcomed the agreement. But how long the ceasefire will hold is the key question, as both Israel and Hezbollah have maintained their right to defend themselves if the truce is broken. Here’s our report.Netanyahu called it a “historic” opportunity for peace, though he refused to withdraw his troops from southern Lebanon during the pause in fighting. “We are remaining in Lebanon in an expanded security zone,” he said, due to the “danger of an invasion” and to prevent fire into Israel. “That is where we are, and we are not leaving.” The Israeli prime minister maintained that his key demand was dismantling Hezbollah. He has previously declared his intention to occupy southern Lebanon up to the Litani River – about 30km from the border – while Lebanon demands the complete withdrawal of Israeli forces and for displaced residents to be able to return to their homes.Iran’s foreign ministry spokesperson Esmail Baghaei welcomed the ceasefire and stressed it was already part of the original Iran-US agreement brokered by Pakistan. Baghaei said Iran emphasised “from the outset” the need for a “simultaneous ceasefire throughout the region, including Lebanon”, and expressed his “solidarity” with the people and government of Lebanon. He called for the return of displaced residents to their homes and emphasised the necessity of the “complete withdrawal” of Israeli forces from the south of the country – which, as mentioned, Israel has refused to do.The Lebanese army urged residents to “exercise restraint” in returning to their villages and towns in southern Lebanon ahead of the ceasefire coming into effect. The army added that even then residents should avoid areas that remain occupied by Israeli forces. It was followed by a similar statement issued by Hezbollah, urging caution amid Israel’s history of “breaking covenants and agreements”.The Israeli military issued an urgent warning to the people of southern Lebanon not to return south of the Litani River despite the ceasefire coming into force.In the hours before the truce took effect, Israel and Hezbollah continued to exchange fire. Just as the ceasefire came into force, the Israeli military said it had hit more than 380 Hezbollah targets in southern Lebanon in the past 24 hours, including rocket launchers, headquarters and Hezbollah members themselves. Meanwhile, Israeli strikes on Lebanese towns and villages killed dozens of people, including an attack on the town of Ghazieh which killed at least seven people and wounded 33, the health ministry said on Thursday. Continue reading...
• NBC News reports a major study shows fluoride in U.S. drinking water has no impact on children's IQ or brain function, countering prior concerns.
• The research, involving large-scale data analysis, confirms safety levels set by U.S. regulations pose no neurodevelopmental risks.
• Findings matter as they support ongoing public fluoridation policies amid debates, potentially easing community health disputes.
Republicans had hoped that Trump’s 2025 tax cuts would be at the forefront of voters’ minds, but many have reportedly not noticed a differenceSign up for the Breaking News US emailHello and welcome to the US politics live blog.It is Tax Day and Republicans are ramping up their efforts to highlight last year’s sweeping tax cuts and turn them into political capital.Eric Swalwell officially resigned from Congress amid the threat of an expulsion vote and other misconduct allegations he has denied. A special election to fill his vacant seat will be held 18 August. At a Los Angeles press conference this morning, Lonna Drewes accused Swalwell of drugging and raping her in 2018, telling reporters she “did not consent to any sexual activity.”The House still needs to pass a bill to fund several Department of Homeland Security (DHS) subagencies, like the Transportation Security Administration (TSA) and the Coast Guard, amid a record-breaking partial government shutdown. The Senate advanced measure that remedies this funding lapse, but doesn’t include money for Immigration and Customs Enforcement (ICE) and border patrol, has stalled in the lower chamber.Meanwhile, House Democrats on Tuesday proposed creating a commission that would work with JD Vance to remove Donald Trump from office under the 25th amendment, should they determine he is no longer fit to serve. The measure, introduced by Jamie Raskin, the top Democrat on the House judiciary committee, follows a series of statements from Trump, including his recent warning that Iran’s “whole civilization will die” if it did not capitulate to his demands, and a social media post that depicted him as Jesus Christ.Donald Trump has said that talks with Iran could resume in Pakistan over next two days, according to an interview with the New York Post. “You should stay there, really, because something could be happening over the next two days, and we’re more inclined to go there,” Trump was quoted as saying.The US state department said Tuesday that Israel and Lebanon have agreed to launch direct negotiations at a mutually agreed-upon time and place. The state department “expressed hope” that the meeting between Israel and Lebanon would “lead to peace agreement”.The Senate will hold its confirmation hearing for Kevin Warsh, the president’s pick to fill the vacant seat of Federal Reserve chair, next week, on 21 April. Both Republicans and Democrats on the Senate Banking Committee are expected to probe Warsh about his wealth and ties to convicted sex offender Jeffrey Epstein, as well as his views on the Fed’s independence.The justice department has asked a federal appeals court to throw out the seditious conspiracy convictions of several leaders of the Proud Boys and Oath Keepers, who were involved in the January 6 attack on the US Capitol. In a court filing today, the department asked the US Court of Appeals for the District of Columbia Circuit to vacate the convictions – a step further than moves Donald Trump made to commute the leaders’ prison sentences last January when he granted clemency to all defendants charged in the attack. Continue reading...
Adelaide has the biggest price decline, with unleaded down 24.9 cents and diesel down 21.3 centsFollow our Australia news live blog for latest updatesGet our breaking news email, free app or daily news podcastFuel prices have started falling immediately across Australia in the wake of the government’s fuel excise cut, unexpectedly accelerating the delivery of the Albanese government’s cost-of-living relief.Prices in capital cities paused then plummeted on Wednesday, after the prime minister announced the tax on petrol and diesel would be halved to 26.3 cents a litre. Continue reading...
• The Federal Deposit Insurance Corporation announced rescission of its Statement of Policy on Qualifications for Failed Bank Acquisitions, effective March 23, 2026.
• The move simplifies regulatory approach to bank resolutions amid ongoing financial policy adjustments under the Trump administration.
• A Phase 2 clinical trial led by Memorial Sloan Kettering Cancer Center demonstrated that engineered CAR-T cells targeting mesothelin showed a 52% overall response rate in 89 patients with advanced pancreatic and ovarian cancers.
• The trial, results published March 19 in Cancer Cell, showed durable responses lasting over one year in 68% of responding patients, compared to historical response rates below 20% with conventional chemotherapy.
• CAR-T therapy has revolutionized blood cancer treatment but remained ineffective against solid tumors until recent engineering advances, potentially opening a new therapeutic avenue for 400,000 Americans diagnosed with pancreatic and ovarian cancers annually.
Britain authorises use of military bases to strike Iranian missile launchers that target shipping in strait of HormuzPresident Trump branded the UK and other Nato allies “cowards” on Friday amid growing anger among cabinet ministers that his war in Iran could jeopardise Britain’s fragile finances. Senior members of the government are in despair about the potential effects on the economy, with experts warning of higher energy prices and mortgage and borrowing costs. They have already begun contingency planning in case the conflict is protracted – lowering speed limits to minimise fuel consumption is among the measures that could be considered by transport officials.With conflict continuing to escalate, the UK confirmed it was now authorising the use of British military bases to strike Iranian missile launchers that are targeting commercial ships in the strait. Continue reading...
• The EPA issued a final rule on February 27, 2026, adding sodium perfluorohexanesulfonate (PFHxS-Na) to the list of chemicals subject to toxic chemical release reporting under the Emergency Planning and Community Right-to-Know Act.
• The rule implements a mandate from the National Defense Authorization Act for Fiscal Year 2020 and requires reporting for chemicals subject to the Pollution Prevention Act beginning with reporting year 2026.
• The final rule becomes effective March 30, 2026, and the EPA determined notice-and-comment rulemaking was unnecessary as the action conforms regulations to Congressional legislative mandate.
International researchers find ‘very little evidence’ medical form of the drug can treat anxiety, anorexia and other disordersCannabis is not an effective treatment for common mental health conditions despite the global surge in patients using it for that purpose, a review has found.Researchers concluded there was “very little evidence for its efficacy” in treating anxiety, anorexia nervosa, psychotic disorders, post-traumatic stress disorder or opioid use disorder. Continue reading...
Corporation’s lawyers argue expensive but ‘groundless’ litigation restricts ability to cover public figuresThe BBC has asked a US court to throw out Donald Trump’s $10bn (£7.5bn) lawsuit over the way a documentary edited one of his speeches, warning that proceeding with the case would have a “chilling effect” on its reporting on the president.In papers filed to the Florida court dealing with the case, the BBC’s US lawyers claimed Trump’s reputation had not been damaged by the documentary, given it aired in the UK a week before his re-election. Continue reading...
Swift leads with 1.6m vinyl sales of The Life of a Showgirl in 2025 while Sabrina Carpenter and Kendrick Lamar round out the LP chartsFor the first time in over four decades, US vinyl sales have topped $1bn in annual revenue.Vinyl purchases reached $1.04bn in 2025, per a new report by the Recording Industry Association of America (RIAA) published on 16 March. It marks the 19th consecutive year of growth for the format that was once considered a niche interest. Continue reading...
The 2025-2026 flu season is concluding with one of the lowest vaccine effectiveness rates in more than a decade, with the CDC reporting effectiveness of approximately 25-30% in preventing adults from needing medical care, according to data released Friday. A viral mismatch between the vaccine strain and dominant H3N2 variant that emerged early winter caused the poor performance, with vaccination proving more protective in children at around 40% effectiveness against medical visits. Despite low effectiveness, the CDC estimates 27 million illnesses, 350,000 hospitalizations, and 22,000 deaths from flu this season—substantially lower than the prior year's 40 million illnesses and 520,000 hospitalizations at the same point.
CDC interim analysis from September 2025 to February 2026 shows this season's flu vaccine effectiveness at 22-34% against outpatient visits for adults and 30-41% for those 65+, with hospitalization protection at 30-31%, due to H3N2 strain mismatch. The season saw 27 million illnesses, 350,000 hospitalizations, and 22,000 deaths, lower than last year's peaks but with 101 child deaths, 85% unvaccinated. Despite flaws, experts like Dr. William Schaffner stress shots prevent severe outcomes, with adult rates at 46.5%. Vaccination campaigns will target improved strains for next season.
CDC studies from September 2025 to February 2026 estimate flu vaccine effectiveness (VE) at 22-34% against influenza A/B outpatient visits for adults and 30-41% for those 65+, with 30-31% against hospitalizations. Patrick Maloney, PhD, from CDC's National Center for Immunization and Respiratory Diseases, led the analysis. Low VE underscores need for improved formulations amid slumping protection. Findings inform next season's vaccine development.