Experimental first-in-class heart drug may also help heal kidneys
• UCLA researchers have developed an experimental drug called AD-NP1, designed to block the protein ENPP1 to prevent heart failure and promote heart tissue healing after a heart attack. • New lab experiments indicate the drug may also be effective for kidney repair, as biopsies from patients with chronic kidney disease show elevated levels of the same ENPP1 protein. • This discovery is significant because it suggests a potential first-in-class treatment for multiple organ systems, expanding the drug's therapeutic potential beyond cardiology.
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