Identify

• Researchers at Binghamton University, State University of New York, along with colleagues at the University of Virginia, published a study in Science Advances mapping innovation landscapes to identify disruptive studies and patents that challenge existing scientific paradigms. • The method, developed by Sadamori Kojaku and colleagues, helps pinpoint discoveries that reshape the course of science, such as the theory of evolution, atomic splitting, and antibiotic development. • The robust measure of disruptiveness provides a systematic way to identify simultaneous breakthroughs across scientific fields and could accelerate recognition of transformative research.

• Scientists have discovered a molecular mechanism that explains the effectiveness of exercise in reversing age-related muscle deterioration. • The finding provides new insight into the cellular processes through which physical activity combats muscle aging at the molecular level. • This breakthrough could lead to targeted therapies mimicking exercise benefits for individuals unable to maintain regular physical activity.

• UC Davis researchers created a new blood test to quickly detect the active, infectious form of tuberculosis, aiming to accelerate diagnosis and curb spread. • TB killed 1.23 million globally in 2024, with over 10,000 U.S. cases including 2,000 in California; the test targets high-burden areas like India. • Professor Imran H. Khan submitted trial data to India's ICMR for approval and co-founded AppGenex Diagnostics to commercialize it.