Lowering

• Merck has received FDA approval for Lipfendra, the first oral pill in the PCSK9 inhibitor class of cholesterol-lowering medications. • Unlike traditional PCSK9 inhibitors that require injections, Lipfendra is a macrocyclic peptide specifically designed for oral administration. • This development provides a more convenient alternative for patients who require stronger cholesterol management than standard statins can offer.

• The FDA has approved Lipfendra, a new cholesterol-lowering pill developed by Merck. • Unlike traditional statins, Lipfendra is a PCSK9 inhibitor, utilizing a different mechanism to reduce cholesterol levels in patients. • This approval provides a new oral therapeutic option for managing high cholesterol, offering an alternative for those who may not respond well to statins.

• The House of Representatives has given final approval to a landmark housing bill designed to increase the housing supply and lower costs. • The legislation provides funding to convert abandoned infrastructure into residential spaces and creates a framework for reforming outdated zoning regulations that currently limit large-scale developments. • Key provisions include raising financing limits for public housing renovations and codifying a recovery program to expedite funding for communities rebuilding after disasters.

President is demanding Senate approve Save America Act, which would dramatically change voting regulationsSign up for the Breaking News US newsletter emailDonald Trump abruptly shelved plans to sign a broad bipartisan bill aimed at lowering the cost of housing on Wednesday, demanding Congress approve his controversial legislation to overhaul US election rules and regulations.The president is pushing the US Senate to approve the Save America Act, which would dramatically change voting regulations by requiring proof of citizenship at voter registration and significantly curtail mail-in voting. Continue reading...

Donald Trump has indicated he will sign rare bipartisan initiative to tackle affordability after 358-32 vote in HouseThe House gave final approval on Tuesday to a broad bipartisan bill aimed at lowering the cost of housing, with lawmakers in both parties eager to show progress on affordability issues ahead of this year’s midterm elections.The 358-32 vote sends the bill to Donald Trump, who is expected to sign it into law on Wednesday at the Capitol. The Senate passed the legislation 85-5 on Monday. Continue reading...

• A new study reveals flowering plants underwent whole-genome duplication in nine distinct bursts across 150 million years to survive environmental crises. • One key event occurred 66 million years ago during the dinosaur-killing meteor impact, transforming plants into 'hopeful monsters' for better adaptation. • These rapid evolutionary shifts highlight plants' resilience, informing modern conservation amid climate change and biodiversity loss.

International Energy Agency recommends emergency measures, including working from home, as Iran war hits fuel supplyLowering speed limits to minimise fuel consumption is among potential contingency plans being drawn up by the UK government as the crisis in the Middle East threatens global oil supplies.Sources stressed that there is no shortage of fuel in the UK, but said that officials in the Department for Transport are working with the Department for Energy Security and Net Zero (DESNZ) on an analysis of how what measures could be taken to curb oil demand. Continue reading...