Prevention

• The city of El Obeid in North Kordofan, Sudan, faces an imminent ground offensive by the Rapid Support Forces (RSF) and their allies after 18 months of siege-like conditions. • Credible reports indicate a high risk of atrocity crimes and widespread human rights violations as the conflict intensifies in the region. • This escalation underscores the urgent need for international intervention to prevent mass atrocities and ensure accountability for perpetrators.

• The UN's top humanitarian official has allocated $8 million to assist Burundi and South Sudan in preparing for the potential spread of Ebola. • Despite increased laboratory capacity from the WHO and Africa CDC, the UN is urging donors to provide more funding to sustain life-saving humanitarian assistance. • UNICEF issued a statement of condolence after an explosive device in the village of Raybi, Yemen, killed five children and injured seven others.

• The U.S. FDA has approved ensitrelvir (Xocova), an oral antiviral developed by Shionogi, for the post-exposure prevention of COVID-19. • The medication is authorized for use in individuals aged 12 years and older who have been exposed to the SARS-CoV-2 virus. • This approval is significant as Xocova becomes the first and only oral medication specifically authorized to reduce the risk of infection after a known exposure.

• The FDA has approved Shionogi’s Xocova (ensitrelvir) as the first oral therapy designed to prevent Covid-19 after a person has been exposed to the virus. • The approval follows the Scorpio-Pep trial involving 2,387 participants aged 12 and older who were asymptomatic but had been exposed to a symptomatic household member. • The drug works by inhibiting viral replication, offering a critical new preventative tool for those who initiate treatment within 72 hours of their contact's symptom onset.

• Evardi Energy, co-founded by UC Berkeley economics and cognitive science student Diva Bhartesh Shah, launched an AI platform to predict electricity demand surges and prevent blackouts. • The system uses machine learning to forecast peak loads up to 48 hours in advance, enabling grid operators to adjust supply dynamically and reduce outage risks by 70%. • This innovation addresses vulnerabilities in aging power infrastructure, potentially saving utilities $billions annually in downtime costs amid rising climate-driven demand.

• A new suicide prevention strategy shifts focus from crisis intervention to upstream policies designed to give people reasons to live and address root causes of suicide risk. • The approach has demonstrated effectiveness in helping individuals in acute distress, including a farmer profiled by CBS News who benefited from this comprehensive intervention model. • This prevention philosophy represents an evolving understanding of mental health intervention that emphasizes long-term resilience and life satisfaction over immediate crisis management.

• The Military Health System's March 26, 2026 update covers research submissions and awards for the Department of War’s primary scientific gathering during March 23-27. • Features teamwork and tools for field medic training, plus new research on preventing dangerous diseases in U.S. Army and Navy contexts. • Army Reserve 'Connect to Protect' initiative emphasizes health protections amid weekly military medical news.