Rounds June

• The Centers for Medicare & Medicaid Services (CMS) has proposed a new rule to establish a permanent framework for its Medicare drug price negotiation program. • Scheduled to begin in 2029, the program focuses on negotiating and renegotiating prices for expensive, single-source drugs to reduce costs for millions of patients. • This move is significant as it aims to provide drug manufacturers with greater long-term certainty while increasing the affordability of critical medications.

• Researchers have developed a new urine test that identifies children likely to have autism by analyzing specific gut microbe profiles. • According to a study published in Molecular Psychiatry, the test correctly identified 90% of autistic children without misidentifying any neurotypical children. • This development matters because it may allow for earlier diagnosis than current assessment tools, potentially leading to faster intervention.

• US-Iran war talks remain clouded by uncertainty as both Washington and Tehran issue conflicting messages regarding the status of negotiations. • In Lebanon, fighting persists between Israel and Hezbollah, indicating that the fragile ceasefire agreement is failing to hold. • Prime Minister Benjamin Netanyahu visited Shlomi in northern Israel on Thursday, reaffirming his commitment to border security while emphasizing a diplomatic approach of flexibility and firmness.