Scientists Develop

• UK scientists from the University of Oxford and biotechnology firm Basecamp Research have launched human trials for the world's first AI-designed vaccine. • The vaccine targets Crimean-Congo haemorrhagic fever (CCHF), a potentially fatal viral disease primarily transmitted to humans via tick bites. • This milestone represents a significant shift in medical research, demonstrating how artificial intelligence can accelerate the design and development of complex drugs.

• MIT researchers discovered that chaotic laser light can self-organize into a highly focused 'pencil beam' under precise conditions, enabling rapid 3D imaging of the blood-brain barrier. • The new method images at speeds 25 times faster than current techniques and tracks drug movement into brain cells in real time. • This breakthrough could accelerate treatments for neurological diseases by allowing high-precision observation of protein absorption in cells.

Oxford team’s technology picked up danger signs with 86% accuracy in study of 72,000 patients in EnglandOxford scientists have developed a simple AI tool that can predict the risk of heart failure five years before it develops.More than 60 million people worldwide have the condition in which the heart cannot pump blood around the body as well as it should. Spotting cases before they develop into heart failure would be a big step forward, experts say. Doctors could prepare better for and manage the condition at an earlier stage or even prevent it entirely. Continue reading...

Bread and biscuits made from Crispr-edited wheat showed substantially reduced acrylamide levels, even after toastingGene-edited wheat which can make bread less carcinogenic when toasted has been successfully developed by scientists.Researchers at Rothamsted Research in Harpenden, Hertfordshire, used Crispr genome editing which allows researchers to selectively edit the DNA of living organisms. This revolutionary technology was adapted for use in the laboratory from naturally occurring genome editing systems found in bacteria. Continue reading...

• Researchers at Binghamton University, State University of New York, along with colleagues at the University of Virginia, published a study in Science Advances mapping innovation landscapes to identify disruptive studies and patents that challenge existing scientific paradigms. • The method, developed by Sadamori Kojaku and colleagues, helps pinpoint discoveries that reshape the course of science, such as the theory of evolution, atomic splitting, and antibiotic development. • The robust measure of disruptiveness provides a systematic way to identify simultaneous breakthroughs across scientific fields and could accelerate recognition of transformative research.