Studying

• A recent New England Journal of Medicine (NEJM) pragmatic trial tested a 6-month rifampicin-resistant tuberculosis (RR-TB) regimen, establishing a new benchmark for adaptive evidence generation. • The trial embedded randomization directly into existing treatment infrastructure to bypass the lengthy 18-month site qualification and rigid eligibility criteria typical of conventional Phase 3 development. • This approach addresses a critical public health crisis, as the WHO Global Tuberculosis Report 2025 estimates 390,000 new MDR/RR-TB cases annually and 150,000 drug-resistant TB deaths in 2024.

• UC San Diego researchers are employing unconventional methods to study space, expanding beyond the university's established history of producing astronauts like Jessica Meir and Kate Rubins. • Professor Karin Sandstrom of the School of Physical Sciences is specifically analyzing the interstellar medium to understand how gas and dust become dense and cold. • This research is critical for uncovering the fundamental mechanisms that trigger the formation of new stars within the universe.