Tide

Medications that target depression, anxiety and poor sleep could help treat pain without opioids’ addictive propertiesA range of other medications could serve as alternatives to powerful opioids for pain relief in emergency departments, according to a new study.The review paper examined non-opioid medications available in the emergency department at San Francisco general hospital and examined existing medical literature to figure out which ones might provide pain relief. Continue reading...

Peptides join melatonin, cannabis and weight loss medications as priority concerns. Follow today’s news liveGet our breaking news email, free app or daily news podcastGood morning and welcome to our live news blog. I’m Martin Farrer with the top overnight stories and then it will be Nick Visser with the main action.A non-profit organisation that runs a helpline for young people says there is little sign of a dip in cyberbullying or image-based abuse in the six months since teenagers under 16 have been banned from social media. More coming up. Continue reading...

Plan promotes ‘deprescribing’ as psychiatrists warn crisis stems from lack of access to care, not overuseThe federal health department will begin a series of steps intended to curb antidepressant use in the US, Robert F Kennedy Jr announced this week.Antidepressants, specifically selective serotonin reuptake inhibitors, have long been a target for Kennedy, the Trump administration’s health secretary, who talked about the plans at an event Monday hosted by the Make America Healthy Again Institute, an organization focused on advancing the MAHA agenda. He has claimed without evidence that the drugs are linked to a rise in school shootings and has expressed concerns about weaning off the medications and withdrawal symptoms. Continue reading...

• The Environmental Protection Agency has classified microplastics and antidepressants as drinking water contaminants, responding to advocacy from the MAHA movement and public health concerns. • The classification marks a significant regulatory step in addressing emerging contaminants in U.S. water supplies that have raised concerns among health experts and environmental advocates. • The designation may prompt future regulatory actions to establish drinking water standards and treatment requirements for these substances.

Prime minister says number of people charged has risen by 17% and technology is helping police to tackle theftKeir Starmer has claimed the “tide could be turning” on shoplifting, pointing to a 17% rise in people charged for what has become a hot political issue.CCTV footage that could be shared immediately with the police should be used more widely, the prime minister said, adding that “the hope of technology” could make a difference. Continue reading...

With the EU approving a €90bn loan for Ukraine, a surprise visit from Prince Harry, and data suggesting Russian troops made almost no territorial gains in March – are there reasons for optimism in Kyiv? Lucy Hough speaks to senior international correspondent Luke Harding – watch on YouTube Continue reading...

• Combination therapy of ixekizumab and tirzepatide yields better results in psoriatic arthritis patients compared to ixekizumab alone, per recent medical research. • This finding advances treatment options for the chronic inflammatory condition affecting joints and skin. • Updated clinical approaches could enhance patient quality of life and disease management.

Exclusive: Guardian investigation finds several clinics making potentially unlawful claims about benefits of unregulated therapiesWhat are peptides, are they safe and is there evidence to back up the hype?The medicines regulator is investigating whether UK clinics are breaking the law by making claims about the benefits of unregulated, experimental peptide therapies, the Guardian can reveal.Interest in experimental peptides has boomed in recent years. The substances are delivered by injection and are touted by sellers, influencers and even some medics as aiding everything from anti-ageing to recovery from injury. Continue reading...

Influencers and athletes are among those claiming substances can help with injury repair, weight loss and angi-ageingMedicines watchdog to investigate UK peptide clinics over health claims From influencers to athletes, high-profile figures are hailing peptides as the route to wellness, claiming they help with injury repair, weight loss, anti-ageing and mood. We take a look at what these substances are, and the murky industry surrounding them. Continue reading...

With two unprecedented trial defeats, big tech firms face crisis akin to that faced by cigarette makers in the 1990sIn the span of just two days, the most powerful social media company in the world faced a more severe public reckoning than it has in years.Jurors in California and New Mexico gave back-to-back verdicts this week that for the first time ever found Meta liable for products that inflict harm on young people. For years, lawmakers, parents and advocates have raised red flags over how social media can hurt children, but now the tech firms are being held to account via court rulings that could set long-lasting precedents. Continue reading...