Genesis Mission

• The U.S. Department of Energy's Genesis Mission, led by Dr. Dario Gil (formerly IBM senior vice president), is deploying AI supercomputing infrastructure to transform American science and engineering across fusion, energy, and national security. • Argonne National Laboratory will deploy approximately 10,000 state-of-the-art GPUs this year via Nvidia and Oracle, with a comparable AMD-HPE cluster launching at Oak Ridge National Laboratory in Tennessee, and a planned 100,000-GPU cluster at Argonne in 2027. • The mission aims to produce 50 to 100 comparable breakthroughs across all scientific domains within three to five years, creating a durable platform of AI supercomputers and next-generation quantum computers for the scientific community.

• The U.S. Department of Energy announced $293 million in funding to advance the Genesis Mission's efforts to tackle the nation's most complex science and technology challenges. • The funding represents a significant federal commitment to supporting breakthrough scientific research and innovation across multiple fields.

The Trump administration announced the Genesis Mission on March 13, 2026, aiming to leverage AI and emerging technologies across energy, drug discovery, national security, and science in the US. Key ambitions include quantum computing advances, expanding the trained technical workforce, and delivering a new supercomputer blueprint by the end of 2026, with involvement from Dell CEO Michael Dell and Energy Department officials. This initiative ties AI policy to tangible outcomes like energy systems and defense, creating opportunities for startups in scientific AI and industrial software. Federal investments in compute and national labs are expected to boost US competitiveness against global rivals.