Loss

• Researchers led by Professor Silvia von Karstedt discovered that loss of Caspase 8 protein in small cell lung cancer triggers inflammation promoting tumor growth and spread. • The study, published in Nature Communications on March 25, 2026, shows this loss reprograms cancer cells into an aggressive neuron-like state associated with relapse. • Findings from the CECAD Cluster of Excellence explain the cancer's notorious aggressiveness and poor prognosis.

• House Republicans announced an investigation into rampant hospice fraud in Southern California, alleging tens of millions in taxpayer funds lost to improper payments. • The House Oversight Committee sent a letter to Governor Gavin Newsom requesting documents on state oversight of federally funded hospice programs. • Fraud involves companies receiving payments for ineligible patients, prompting calls for stronger controls amid ongoing healthcare waste concerns.

• The S&P 500 fell 1.51% to close at 6,506.48, the Nasdaq dropped 2.01% to 21,647.61, and the Dow declined 0.96% to 45,577.47 on Friday, marking the fourth consecutive weekly loss. • Iran conflict pushed oil prices higher, intensifying inflation expectations and prompting investors to reassess Federal Reserve rate-cut bets; rate futures now suggest potential rate increases rather than cuts by 2026. • Major tech stocks suffered significant losses, with Nvidia and Tesla falling over 3%, while Super Micro Computer plunged 33% following smuggling charge reports linked to AI technology exports.

Cryptocurrency’s biggest Pac spent more than $10m for their candidates, only to be defeated by those who are anti-cryptoSign up for the Breaking News US email to get newsletter alerts in your inboxThe cryptocurrency industry spent big and lost often in this week’s Illinois primaries.As the industry prepares to make massive donations in the 2026 midterm elections to replicate its success in 2024, the Illinois losses mark an early setback for firms that are trying to establish themselves as power players in American politics. Continue reading...

He had IRGC’s trust while having his differences with hardliners and had huge sway with likes of China and RussiaMiddle East crisis – live updatesIf confirmed, Israel’s assassination of Ali Larijani, the secretary of Iran’s supreme national security council and one of the linchpins of Iranian politics, would be a devastating body blow to the country and probably a bigger reverse than the loss of the supreme leader Ali Khamenei at the outset of the war.In any attempt to decapitate the Iranian leadership, Larijani would always be the prime target, largely because of his ability to straddle so many levels of Iranian politics and his huge personal influence not just in Iran but with foreign states including China and Russia. Continue reading...

• President Donald Trump launched a series of social media posts on Sunday night criticizing the U.S. Supreme Court as having 'RANSACKED' the country after it rejected his tariffs decision. • Trump acknowledged potential backlash, stating 'This statement about the United States Supreme Court will cause me nothing but problems in the future, but I feel it is my obligation to speak the TRUTH,' amid broader losses including failed prosecutions and coalition splits over Iran war. • The outbursts highlight Trump's frustration with judicial setbacks, such as U.S. District Judge James Boasberg tossing a grand jury subpoena against Fed Chair Jerome Powell on Friday.

• The S&P 500 declined 1.6% last week, marking its third consecutive weekly drop, with the Dow falling 2% and Nasdaq shedding 1.3% due to soaring oil prices and broad market selling. • Surging oil prices from geopolitical tensions, including US-Iran escalation, drove the downturn, as investors brace for NVIDIA GTC AI event and FOMC rate decision this week (March 16-20, 2026). • Markets now price only a 33% chance of a June rate cut, down from 57% last month, amid persistent inflation data; Thursday's jobless claims will gauge labor market health.