Toxicity

• Cast members of the film *Your Fault: London* discussed the complexities of online fame and the tendency for audiences to romanticize toxic relationships. • The production has seen massive global success, ranking number one in over 170 countries upon its release. • Amazon reported in February that the film's reach is predominantly international, with more than 90% of viewers residing outside of Spain.

• The Broad Institute is leveraging artificial intelligence to accelerate drug discovery, designing new antibiotics and predicting drug toxicity with greater accuracy than traditional methods. • The AI systems are also being applied to identify specific genes, molecules, and cells that might serve as therapeutic targets for disease treatment. • This computational approach promises to dramatically speed up the drug development pipeline and reduce the cost and time required to bring new medications to patients.