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• NanoViricides will begin a clinical trial next week for the oral drug NV-387 to treat an expanding Ebola outbreak in the Democratic Republic of Congo. • The current outbreak of the Bundibugyo Ebolavirus variant has a 48% crude fatality rate and no approved treatment or vaccine. • The virus has spread into displacement camps hosting over 4.4 million people, creating a high-risk population with poor sanitation and medical resources.

• Clinical trials for the oral drug NV-387 will begin to treat a rapidly expanding outbreak of the Bundibugyo Ebolavirus in the Democratic Republic of the Congo. • The virus has spread into displacement camps hosting over 4.4 million people who lack adequate drinking water, sanitation, and medical resources. • This trial is critical because there is currently no approved treatment or vaccine for this specific variant of the Ebolavirus Disease.

• India's market regulator, Sebi, is considering weakening or abandoning its recent market-closing auction reform after facing investor backlash and volatility. • The reform was originally designed to curb price manipulation during the final minutes of trading. • A retreat from this policy highlights systemic issues for traders, including high securities taxes, shallow liquidity, and restrictions on short selling.

• The Euro fell below 1.1600 against the US Dollar on Friday as the initial market reaction to a European Central Bank interest rate hike faded. • Traders are shifting focus toward the upcoming Consumer Price Index (CPI) release from the US Department of Labor Statistics. • This currency shift affects international trade costs and investment returns for professionals managing assets in both Euro and Dollar denominations.

• EU foreign policy chief Kaja Kallas recently told The Irish Times that the European Union should treat Israeli settlements similarly to Russian-occupied Crimea. • Kallas argued that implementing an EU-wide trade ban on goods from these occupied territories would be a principled stand. • France announced this week it will pursue a national trade ban, joining the UK, Canada, Spain, the Netherlands, Belgium, and Ireland.

• Asian stock markets declined on Thursday following a retreat on Wall Street and rising energy costs. • Crude oil prices traded above $100 a barrel while Hong Kong's Hang Seng index fell 1.5% to 24,909.58. • High oil prices and falling shares create volatility for global investors and increase operational costs for businesses.

• NanoViricides announced on September 8, 2026, that it has registered a Phase II clinical trial for NV-387 oral gummies to treat the Bundibugyo ebolavirus outbreak in the Democratic Republic of Congo. • The company reports that NV-387 previously performed better than the drug Remdesivir in a lethal animal model of a viral disease. • This trial addresses a critical gap in healthcare because there is currently no approved vaccine or treatment for the specific strain of ebolavirus causing the expanding outbreak.

• NanoViricides announced on September 8, 2026, that it registered a Phase II clinical trial for NV-387 oral gummies to treat the Bundibugyo Ebola virus. • The trial is listed in the Pan African Clinical Trials Database to address the expanding Ebola outbreak in the Democratic Republic of Congo. • This development provides a potential oral treatment option for patients in a region currently facing the largest Ebola outbreak on record.

Reports of Soho Farmhouse visit add to speculation Duke and Duchess of Sussex could be settling in the areaWhen the Duke and Duchess of Sussex landed back in England earlier this summer, six years after they moved to California and quit as working royals, speculation was rife about where they would call home.Now, members of the luxury countryside retreat Soho Farmhouse have said they spotted Meghan arriving for an early morning coffee, sparking speculation that the couple were settling down in the exclusive countryside enclave of north Oxfordshire. Correspondent for the Royalist Tom Sykes said the duchess was seen arriving at the Comfy Farm lounge before 9am, where she was introduced to senior staff members by name. Continue reading...

• The FDA approved a new cancer drug from Revolution Medicines last week after founder Greg Verdine spent 14 years developing the treatment. • Former Senator Ben Sasse, who has stage 4 pancreatic cancer, called the daily pill a "miracle" for shrinking his tumor volume and reducing pain. • This approval validates high-risk biotech experiments that target previously untreatable cancer pathways to provide new options for late-stage patients.

• Asian stock markets rose, with South Korea’s KOSPI gaining 1.5% and Singapore’s Straits Times Index increasing by 0.7%, as bond yields retreated and oil prices steadied. • Mitsubishi Corp climbed nearly 5% and financial stocks advanced following comments from Berkshire Hathaway CEO Greg Abel, who reaffirmed the firm's long-term commitment to Japanese investments. • The rally is driven by Berkshire Hathaway's existing 10%+ stakes in major Japanese trading houses and signals that the conglomerate may further increase these holdings.

• Asian stock markets rose, with South Korea’s KOSPI advancing 1.5% and Singapore’s Straits Times Index gaining 0.7%, as bond yields retreated and oil prices steadied. • Mitsubishi Corp climbed nearly 5% and financial stocks surged following comments from Berkshire Hathaway CEO Greg Abel, who reaffirmed the firm's long-term commitment to its Japanese investments. • The rally was bolstered by Berkshire Hathaway's existing 10%+ stakes in major Japanese trading houses and signals that the conglomerate may increase these holdings.

• On Monday, August 31, the Permanent Court of Arbitration (PCA) in The Hague ruled that India cannot unilaterally suspend the Indus Waters Treaty. • The five-member tribunal issued a unanimous decision rejecting all arguments presented by New Delhi since April 2025 to justify the suspension. • This ruling is critical for South Asia's water security, as the treaty governs the distribution of vital river waters between India and Pakistan.

• Iceland held a referendum in which 52.8% of voters rejected the proposal to resume accession talks with the European Union. • The EU maintained a largely silent stance throughout the campaign, a strategy that mirrors its muted response during the UK's Brexit vote a decade ago. • This result signifies a continued lack of appetite within Iceland to join the bloc, reinforcing the country's current independent status.

• NanoViricides, Inc. (NYSE American: NNVC) announced on August 31, 2026, that it is preparing for clinical trials of its broad-spectrum drug candidate, NV-387. • The drug utilizes host-mimetic nanomedicine technology designed to treat measles, a disease currently seeing a rise in cases both within the USA and globally. • This development is significant as it aims to provide a revolutionary antiviral treatment that viruses cannot easily escape, addressing a critical gap in measles management.

Bureau will still dismiss those engaged with sex workers within past 10 years, three or more times overall, or while in public safety capacityThe FBI is dropping a categorical hiring ban on applicants who have had sexual encounters with sex workers and will instead consider in a more holistic manner at least some candidates who have engaged in the practice in the past, according to people familiar with the matter.The move away from an automatic disqualification falls along a continuum of evolving recruitment standards within federal law enforcement and at the buttoned-up bureau, which several years ago relaxed its approach to candidates’ past marijuana use and has drawn more recent concern among some current and former agents about a perceived loosening of recruitment requirements as it seeks to replenish its ranks. Continue reading...

• Federal Reserve Chair Kevin Warsh signaled on Friday, Aug. 28, 2026, that the central bank may raise interest rates in the coming months. • Speaking at the annual Jackson Hole Economic Policy Symposium, Warsh stated that U.S. inflation remains stubbornly elevated and is still too high. • This announcement represents a clearer and more direct signal regarding his economic outlook than he has provided in previous communications.

• Federal Reserve Chair Kevin Warsh is set to deliver his first major speech during the bank's annual economic retreat in Jackson Hole. • The address serves as a critical platform for Warsh to outline his specific strategy for managing inflation and stabilizing the economy. • This appearance is viewed as a pivotal moment for Warsh to establish his leadership and boost his professional credibility with markets and policymakers.

• Moderna and Merck announced on August 19, 2026, that their personalized mRNA vaccine, intismeran autogene, successfully passed a late-stage clinical trial. • The vaccine was used in combination with the immunotherapy drug Keytruda to effectively reduce the recurrence of melanoma, a form of skin cancer. • This milestone represents a significant breakthrough in oncology, demonstrating the potential for mRNA technology to transform both cancer treatment and prevention.

• Pulnovo Medical has enrolled the first two U.S. patients in its PULSE-LHD clinical trial at Henry Ford Hospital in Detroit. • The trial is conducted under an FDA Investigational Device Exemption (IDE) to evaluate pulmonary artery denervation for treating pulmonary hypertension associated with left heart disease. • This study is significant as it tests a novel medical device approach to managing complex heart failure and pulmonary hypertension conditions.

• Mark Orwig participated in a clinical trial for an mRNA vaccine designed to prevent the recurrence of melanoma after surgical tumor removal. • The treatment targets lingering cancer cells that often remain in the body post-surgery, which typically lead to the disease returning. • Scientists believe this personalized mRNA approach could revolutionize cancer care by transforming how doctors treat high-risk patients.

Treatment is already required by parole boards in several countries, but some feel the practice is unethicalThousands of sex offenders in England and Wales could get libido-suppressing drugsFor some prisoners with problematic sexual arousal (PSA), “images of sex flood their minds” all of their waking hours, according to Prof Belinda Winder, a leading forensic psychologist who has evaluated the use of drugs to control libidos.“I remember talking to one guy a few weeks after he started taking the medication. He said: ‘It’s amazing. I followed a film plot. I wasn’t just looking for when I could see bra straps, when I could see nipples, when someone’s going to bend over so I could see their bum.” Continue reading...

• Moderna and Merck have reported positive results from a large Phase 3 clinical trial of a personalized mRNA-based cancer vaccine designed to treat melanoma. • Unlike traditional treatments, this therapy trains a patient's own immune system to recognize and destroy the specific cancer cells threatening them. • This breakthrough represents a major step forward in precision oncology, moving away from broad attacks on cancer cells toward highly targeted immunotherapy.

Chester zoo resident, 23, ‘back to her usual feisty self’ after electrochemotherapy for tumour in her jawA 15ft (4.5-metre) python is believed to be the first snake in the world to be given a pioneering, life-saving cancer treatment normally used on humans.The 50kg reticulated python, named Jodie Foster after the Hollywood star, has just turned 23 and lives at Chester zoo. Keepers first became concerned that she may be unwell when she began eating less and spending more time inactive in her habitat. Continue reading...

• The FDA has approved Pasatru™ (garetosmab-grts) as the first and only treatment to reduce new heterotopic ossification (HO) lesions and clinician-assessed flare-ups in adults with Fibrodysplasia Ossificans Progressiva (FOP). • The approval follows the OPTIMA Phase 3 clinical trial, a multinational study designed to evaluate the drug's efficacy, safety, tolerability, and pharmacokinetics in patients with active FOP. • This development is significant as it provides a targeted therapeutic option for a rare disease, supported by previous Fast Track and Orphan Drug designations from the FDA, EMA, and Japan's Ministry of Health.

• Moderna and Merck are developing personalized cancer vaccines designed to train the immune system to target mutations specific to an individual's tumor. • The treatment represents a potential breakthrough in oncology by shifting toward highly tailored immunotherapy rather than one-size-fits-all approaches. • Clinical trial results for colon cancer are anticipated in 2027, with data for pancreatic cancer trials expected to follow by 2031.

• Moderna and Merck announced that an experimental mRNA vaccine effectively prevented skin cancer recurrence in a large-scale clinical trial. • The therapy utilizes the same messenger RNA technology used in COVID-19 vaccines to deliver a customized treatment tailored to a patient's specific tumors. • This development represents a landmark moment in oncology, demonstrating the potential for personalized vaccines to treat and prevent the return of malignant tumors.

• Pakistani authorities have petitioned the Supreme Court to review or withdraw a mandate requiring imprisoned former Prime Minister Imran Khan to undergo a medical examination at a private hospital. • Information Minister Attaullah Tarar stated that while the government does not object to Khan receiving medical care, it challenges the specific requirement to use a private facility over prison-regulated treatment. • The government argues that health issues should remain separate from political disputes and maintains that Khan will continue to be treated according to established prison rules.