Researchers

• Stanford University neuroscientists discovered a blood-based biomarker (phosphorylated tau-217) that reliably predicts Alzheimer's disease development one to two decades before cognitive decline appears, according to research published April 20. • The biomarker was identified through analysis of blood samples from 2,500 cognitively healthy individuals followed for 15 years, with positive predictive value exceeding 92% in early-stage detection. • The finding could enable preventative therapies targeting amyloid and tau proteins before neurodegeneration becomes irreversible, potentially transforming Alzheimer's treatment approaches.

The school’s $100m project to examine its slave ownership in Antigua is mired with controversy as academics allege obstructionChristopher Newman remembers seeing campus police officers as he walked into a human resources office at Harvard University, but he didn’t imagine that they were there for him.It was July 2024, and Newman had just turned in the results of a two-month-long internship with the Harvard University Archives: an annotated bibliography for the landmark 2022 Harvard and the Legacy of Slavery Initiative report, which detailed the university’s ties to slavery across three centuries. He completed his project on Friday, 26 July, and on Monday, he said he received an email that HR wanted to meet with him. Continue reading...

Participants reported enjoying the human connection regardless of whether they thought the topic was dullThe human aversion to dull experiences was nailed by the author Paulo Coelho when he declared: “I can stand defeats, pain, anger. But I can’t stand boredom.”But the natural desire to avoid boring conversations comes at a cost, according to researchers, who found that people enjoyed chatting about tedious topics far more than they expected. Continue reading...

• Climate scientists have discovered that nitrous oxide, a key greenhouse gas, has a shorter atmospheric lifetime than previously modeled, decreasing more rapidly than expected. • This unexpected finding is significantly altering climate projections and forcing researchers to recalibrate their long-term climate models and predictions. • The discovery underscores the importance of continuous monitoring and reassessment of greenhouse gas behavior in the atmosphere, with implications for future climate policy and environmental planning.

• The MajesTEC-3 clinical trial led by UAB researchers demonstrates that a new two-drug immunotherapy regimen can lead to long-lasting remission for multiple myeloma patients. • Over 83 percent of patients enrolled in the trial remain alive and progression-free three years after therapy, supporting approval of this potentially curative treatment. • The findings represent a significant advance for multiple myeloma, a blood cancer with limited treatment options historically.

• Caltech scientists led by Manuel Endres unveiled a theoretical design for neutral-atom quantum computers that slashes required hardware by roughly 100 times, potentially making scalable machines feasible within years. • The breakthrough uses laser-trapped atoms movable across arrays, enabling long-distance connections unlike fixed-qubit systems; Endres noted, 'It’s actually very surprising how well this works,' calling it 'ultra-efficient error correction.' • Last year, the team assembled a record 6,100 atomic qubits, published in Nature, advancing beyond nearest-neighbor limitations in other platforms.

‘There is no doubt that the cells and tissues of the oral cavity, the mouth and the lungs are altered by inhalation from e-cigarettes,’ academic saysGet our breaking news email, free app or daily news podcastVaping is likely to cause lung and oral cancer, researchers have found, as they urged regulators to act now rather than wait decades for a definitive level of risk.Cancer researchers led by UNSW in Sydney analysed reviews of evidence from animal studies, human case reports and laboratory research published between 2017 and 2025, in one of the most detailed assessments to date of whether nicotine e-cigarettes could cause cancer. Continue reading...