Imaging

• MIT 研究人员发现，在精确条件下，混沌激光可以自组织成高度聚焦的“铅笔束”，从而实现血脑屏障的快速 3D 成像。 • 这种新方法的成像速度比现有技术快 25 倍，并能实时追踪药物进入脑细胞的运动过程。 • 这一突破可通过对细胞内蛋白质吸收进行高精度观察，从而加速神经系统疾病的治疗研究。

• Telix Pharmaceuticals resubmitted its New Drug Application to the U.S. FDA on March 16, 2026, for TLX101-Px (Pixclara®), a PET imaging agent targeting gliomas in adults and pediatrics. • The agent received Orphan Drug and Fast Track designations from the FDA due to its potential to address unmet needs in post-treatment glioma management, with 18F-FET PET already in international guidelines but no U.S.-approved equivalent. • Glioblastoma multiforme (GBM), the most common aggressive primary brain cancer, affects about 22,000 new U.S. cases yearly, with recurrence nearly universal and median survival of 12-15 months post-diagnosis.