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• Virginia の有権者は、複数の GOP 現職議員を危うくする Democratic が支持する連邦下院の redistricting 案を僅差で承認しました。 • この措置は、主要な選挙区で Democratic に有利になるよう境界線を引き直すもので、2026 midterm races に向けた勢力均衡を変化させます。 • この沿岸部での redistricting を巡る争いは、公正な地図（fair maps）と党派的な優位性を巡る全米的な緊張を浮き彫りにしています。

• OxyContinの製造元であるPurdue Pharmaは、数千件の訴訟を解決するための包括的な法的和解が効力を発することに伴い、今週末までに解散し、公共の利益に焦点を当てた新会社に置き換えられる予定です。 • 火曜日、連邦裁判官は米国司法省による調査を解決するための刑事判決を同社に下しました。これは、和解への道を切り開くための最終的な必要手順となります。

One Nation outperforms the Coalition for the first time, while the rightwing populist party’s leader has a positive rating among all age groupsGet our breaking news email, free app or daily news podcastA majority of surveyed Australians approve of Pauline Hanson’s leadership of One Nation, giving her a higher job approval rating than Anthony Albanese and Angus Taylor, as the Guardian Essential poll finds the rightwing populist party is outperforming the Coalition for the first time.The results come as Australians are becoming more pessimistic about the country and the economy, with the majority of respondents saying they expected things to get worse in coming months. Continue reading...

Leaders will discuss how to respond to surging energy prices amid the war in the Middle EastEurope live – latest updatesEU leaders have welcomed the end of diplomatic deadlock over a long-awaited €90bn (£78bn) loan for Ukraine, after the bloc finalised the agreement along with a 20th package of sanctions against Russia.After weeks of delay, the EU signed off on the loan on Thursday, in time for summit talks in Cyprus that are scheduled to begin in the evening and will include talks over a dinner with the Ukrainian leader, Volodymyr Zelenskyy. Continue reading...

The merger will still require governmental approval and could be delayed by a lawsuit seeking to block itShareholders of Warner Bros Discovery voted “overwhelmingly” to approve the company’s $110bn merger with Paramount Skydance, the parent company of CBS News, on Thursday.But shareholders voted against generous proposed compensation packages for WBD executives, including a $550m payout to the outgoing chief executive, David Zaslav. Continue reading...

• The FDA granted accelerated approval to a CRISPR-based gene therapy for severe sickle cell disease on April 20, marking the first approved genetic treatment editing patient blood cells to produce functional hemoglobin. • Clinical trials demonstrated 95% of treated patients experienced elimination or near-elimination of vaso-occlusive crises within 12 months, with durable responses observed for over two years post-treatment. • The therapy addresses a disease affecting approximately 100,000 Americans, primarily of African descent, offering potential cure for patients previously reliant on pain management and blood transfusions.