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• 維吉尼亞州選民以微弱優勢通過了一項由民主黨支持的國會重新劃分選區計劃，這將危及數名共和黨現任議員。 • 該措施重新劃定選區線路以利於民主黨在關鍵選區獲勝，從而改變 2026 年中期選舉的平衡。 • 這場沿海地區的劃分選區之爭突顯了全美在公平地圖與黨派利益之間的緊張局勢。

隨著法律和解協議生效，OxyContin 製造商將被一家旨在對抗鴉片類藥物危機的新公司所取代。

One Nation outperforms the Coalition for the first time, while the rightwing populist party’s leader has a positive rating among all age groupsGet our breaking news email, free app or daily news podcastA majority of surveyed Australians approve of Pauline Hanson’s leadership of One Nation, giving her a higher job approval rating than Anthony Albanese and Angus Taylor, as the Guardian Essential poll finds the rightwing populist party is outperforming the Coalition for the first time.The results come as Australians are becoming more pessimistic about the country and the economy, with the majority of respondents saying they expected things to get worse in coming months. Continue reading...

Leaders will discuss how to respond to surging energy prices amid the war in the Middle EastEurope live – latest updatesEU leaders have welcomed the end of diplomatic deadlock over a long-awaited €90bn (£78bn) loan for Ukraine, after the bloc finalised the agreement along with a 20th package of sanctions against Russia.After weeks of delay, the EU signed off on the loan on Thursday, in time for summit talks in Cyprus that are scheduled to begin in the evening and will include talks over a dinner with the Ukrainian leader, Volodymyr Zelenskyy. Continue reading...

The merger will still require governmental approval and could be delayed by a lawsuit seeking to block itShareholders of Warner Bros Discovery voted “overwhelmingly” to approve the company’s $110bn merger with Paramount Skydance, the parent company of CBS News, on Thursday.But shareholders voted against generous proposed compensation packages for WBD executives, including a $550m payout to the outgoing chief executive, David Zaslav. Continue reading...

• The FDA granted accelerated approval to a CRISPR-based gene therapy for severe sickle cell disease on April 20, marking the first approved genetic treatment editing patient blood cells to produce functional hemoglobin. • Clinical trials demonstrated 95% of treated patients experienced elimination or near-elimination of vaso-occlusive crises within 12 months, with durable responses observed for over two years post-treatment. • The therapy addresses a disease affecting approximately 100,000 Americans, primarily of African descent, offering potential cure for patients previously reliant on pain management and blood transfusions.