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• 弗吉尼亚州选民以微弱优势批准了一项由民主党支持的国会选区重划计划，该计划使多名共和党现任议员处于不利地位。 • 该措施通过重新划分关键选区的界线以利于民主党，从而改变了2026年中期选举的平衡。 • 此次沿海地区的选区重划之争凸显了全美范围内关于公平地图与党派优势的紧张局势。

随着法律和解协议生效，OxyContin 制造商将由一家旨在应对阿片类药物危机的新公司取代。• OxyContin 制造商 Purdue Pharma 将在本周结束前被解散，并由一家专注于公共利益的公司取代，此前一项旨在解决数千起诉讼的全面法律和解协议已开始生效。 • 周二，一名联邦法官对该公司下达了刑事判决，以解决美国司法部的一项调查——这是为该和解协议扫清障碍的最后一个必要步骤。阅读详情...

One Nation outperforms the Coalition for the first time, while the rightwing populist party’s leader has a positive rating among all age groupsGet our breaking news email, free app or daily news podcastA majority of surveyed Australians approve of Pauline Hanson’s leadership of One Nation, giving her a higher job approval rating than Anthony Albanese and Angus Taylor, as the Guardian Essential poll finds the rightwing populist party is outperforming the Coalition for the first time.The results come as Australians are becoming more pessimistic about the country and the economy, with the majority of respondents saying they expected things to get worse in coming months. Continue reading...

Leaders will discuss how to respond to surging energy prices amid the war in the Middle EastEurope live – latest updatesEU leaders have welcomed the end of diplomatic deadlock over a long-awaited €90bn (£78bn) loan for Ukraine, after the bloc finalised the agreement along with a 20th package of sanctions against Russia.After weeks of delay, the EU signed off on the loan on Thursday, in time for summit talks in Cyprus that are scheduled to begin in the evening and will include talks over a dinner with the Ukrainian leader, Volodymyr Zelenskyy. Continue reading...

The merger will still require governmental approval and could be delayed by a lawsuit seeking to block itShareholders of Warner Bros Discovery voted “overwhelmingly” to approve the company’s $110bn merger with Paramount Skydance, the parent company of CBS News, on Thursday.But shareholders voted against generous proposed compensation packages for WBD executives, including a $550m payout to the outgoing chief executive, David Zaslav. Continue reading...

• The FDA granted accelerated approval to a CRISPR-based gene therapy for severe sickle cell disease on April 20, marking the first approved genetic treatment editing patient blood cells to produce functional hemoglobin. • Clinical trials demonstrated 95% of treated patients experienced elimination or near-elimination of vaso-occlusive crises within 12 months, with durable responses observed for over two years post-treatment. • The therapy addresses a disease affecting approximately 100,000 Americans, primarily of African descent, offering potential cure for patients previously reliant on pain management and blood transfusions.